Pyrinap ligands for enantioselective syntheses of amines

Chiral amines find use as chiral ligands, resolving reagents and versatile building blocks as well as in pharmaceuticals and agrochemicals. Here, the authors developed Pyrinap ligands for the copper-catalyzed enantioselective A3-coupling of terminal alkynes, aldehydes, and amines affording optically...

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Autores principales: Qi Liu, Haibo Xu, Yuling Li, Yuan Yao, Xue Zhang, Yinlong Guo, Shengming Ma
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fdb9e98aedf14392a53e0f661fadc8fe
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spelling oai:doaj.org-article:fdb9e98aedf14392a53e0f661fadc8fe2021-12-02T15:08:01ZPyrinap ligands for enantioselective syntheses of amines10.1038/s41467-020-20205-02041-1723https://doaj.org/article/fdb9e98aedf14392a53e0f661fadc8fe2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20205-0https://doaj.org/toc/2041-1723Chiral amines find use as chiral ligands, resolving reagents and versatile building blocks as well as in pharmaceuticals and agrochemicals. Here, the authors developed Pyrinap ligands for the copper-catalyzed enantioselective A3-coupling of terminal alkynes, aldehydes, and amines affording optically active propargylic amines.Qi LiuHaibo XuYuling LiYuan YaoXue ZhangYinlong GuoShengming MaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qi Liu
Haibo Xu
Yuling Li
Yuan Yao
Xue Zhang
Yinlong Guo
Shengming Ma
Pyrinap ligands for enantioselective syntheses of amines
description Chiral amines find use as chiral ligands, resolving reagents and versatile building blocks as well as in pharmaceuticals and agrochemicals. Here, the authors developed Pyrinap ligands for the copper-catalyzed enantioselective A3-coupling of terminal alkynes, aldehydes, and amines affording optically active propargylic amines.
format article
author Qi Liu
Haibo Xu
Yuling Li
Yuan Yao
Xue Zhang
Yinlong Guo
Shengming Ma
author_facet Qi Liu
Haibo Xu
Yuling Li
Yuan Yao
Xue Zhang
Yinlong Guo
Shengming Ma
author_sort Qi Liu
title Pyrinap ligands for enantioselective syntheses of amines
title_short Pyrinap ligands for enantioselective syntheses of amines
title_full Pyrinap ligands for enantioselective syntheses of amines
title_fullStr Pyrinap ligands for enantioselective syntheses of amines
title_full_unstemmed Pyrinap ligands for enantioselective syntheses of amines
title_sort pyrinap ligands for enantioselective syntheses of amines
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/fdb9e98aedf14392a53e0f661fadc8fe
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AT yulingli pyrinapligandsforenantioselectivesynthesesofamines
AT yuanyao pyrinapligandsforenantioselectivesynthesesofamines
AT xuezhang pyrinapligandsforenantioselectivesynthesesofamines
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