Pyrinap ligands for enantioselective syntheses of amines
Chiral amines find use as chiral ligands, resolving reagents and versatile building blocks as well as in pharmaceuticals and agrochemicals. Here, the authors developed Pyrinap ligands for the copper-catalyzed enantioselective A3-coupling of terminal alkynes, aldehydes, and amines affording optically...
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Nature Portfolio
2021
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oai:doaj.org-article:fdb9e98aedf14392a53e0f661fadc8fe2021-12-02T15:08:01ZPyrinap ligands for enantioselective syntheses of amines10.1038/s41467-020-20205-02041-1723https://doaj.org/article/fdb9e98aedf14392a53e0f661fadc8fe2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20205-0https://doaj.org/toc/2041-1723Chiral amines find use as chiral ligands, resolving reagents and versatile building blocks as well as in pharmaceuticals and agrochemicals. Here, the authors developed Pyrinap ligands for the copper-catalyzed enantioselective A3-coupling of terminal alkynes, aldehydes, and amines affording optically active propargylic amines.Qi LiuHaibo XuYuling LiYuan YaoXue ZhangYinlong GuoShengming MaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
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Science Q Qi Liu Haibo Xu Yuling Li Yuan Yao Xue Zhang Yinlong Guo Shengming Ma Pyrinap ligands for enantioselective syntheses of amines |
description |
Chiral amines find use as chiral ligands, resolving reagents and versatile building blocks as well as in pharmaceuticals and agrochemicals. Here, the authors developed Pyrinap ligands for the copper-catalyzed enantioselective A3-coupling of terminal alkynes, aldehydes, and amines affording optically active propargylic amines. |
format |
article |
author |
Qi Liu Haibo Xu Yuling Li Yuan Yao Xue Zhang Yinlong Guo Shengming Ma |
author_facet |
Qi Liu Haibo Xu Yuling Li Yuan Yao Xue Zhang Yinlong Guo Shengming Ma |
author_sort |
Qi Liu |
title |
Pyrinap ligands for enantioselective syntheses of amines |
title_short |
Pyrinap ligands for enantioselective syntheses of amines |
title_full |
Pyrinap ligands for enantioselective syntheses of amines |
title_fullStr |
Pyrinap ligands for enantioselective syntheses of amines |
title_full_unstemmed |
Pyrinap ligands for enantioselective syntheses of amines |
title_sort |
pyrinap ligands for enantioselective syntheses of amines |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/fdb9e98aedf14392a53e0f661fadc8fe |
work_keys_str_mv |
AT qiliu pyrinapligandsforenantioselectivesynthesesofamines AT haiboxu pyrinapligandsforenantioselectivesynthesesofamines AT yulingli pyrinapligandsforenantioselectivesynthesesofamines AT yuanyao pyrinapligandsforenantioselectivesynthesesofamines AT xuezhang pyrinapligandsforenantioselectivesynthesesofamines AT yinlongguo pyrinapligandsforenantioselectivesynthesesofamines AT shengmingma pyrinapligandsforenantioselectivesynthesesofamines |
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1718388296036384768 |