Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.

Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.

The factors determining the functional avidity and its relationship with the broad heterogeneity of antiviral T cell responses remain partially understood. We investigated HIV-specific CD8 T cell responses in 85 patients with primary HIV infection (PHI) or chronic (progressive and non-progressive) i...

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Detalles Bibliográficos
Autores principales: Selena Viganò, Felicitas Bellutti Enders, Isabelle Miconnet, Cristina Cellerai, Anne-Laure Savoye, Virginie Rozot, Matthieu Perreau, Mohamed Faouzi, Khalid Ohmiti, Matthias Cavassini, Pierre-Alexandre Bart, Giuseppe Pantaleo, Alexandre Harari
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/fdc4487162b047959a2bf1893a473270
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