IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development

Innate lymphoid cells (ILC) are important regulators of mucosal immunity, but how their development and homeostasis are modulated is still unclear. Here the authors show that the differentiation of group 3 ILCs is controlled by the glutamylation of IL-7Rα and the induction of transcription factor Sa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Benyu Liu, Buqing Ye, Xiaoxiao Zhu, Guanling Huang, Liuliu Yang, Pingping Zhu, Ying Du, Jiayi Wu, Shu Meng, Yong Tian, Zusen Fan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fdcc5a6db53a4add8f579c835b2349d1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fdcc5a6db53a4add8f579c835b2349d1
record_format	dspace
spelling	oai:doaj.org-article:fdcc5a6db53a4add8f579c835b2349d12021-12-02T14:16:47ZIL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development10.1038/s41467-017-00235-x2041-1723https://doaj.org/article/fdcc5a6db53a4add8f579c835b2349d12017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00235-xhttps://doaj.org/toc/2041-1723Innate lymphoid cells (ILC) are important regulators of mucosal immunity, but how their development and homeostasis are modulated is still unclear. Here the authors show that the differentiation of group 3 ILCs is controlled by the glutamylation of IL-7Rα and the induction of transcription factor Sall3.Benyu LiuBuqing YeXiaoxiao ZhuGuanling HuangLiuliu YangPingping ZhuYing DuJiayi WuShu MengYong TianZusen FanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benyu Liu Buqing Ye Xiaoxiao Zhu Guanling Huang Liuliu Yang Pingping Zhu Ying Du Jiayi Wu Shu Meng Yong Tian Zusen Fan IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development
description	Innate lymphoid cells (ILC) are important regulators of mucosal immunity, but how their development and homeostasis are modulated is still unclear. Here the authors show that the differentiation of group 3 ILCs is controlled by the glutamylation of IL-7Rα and the induction of transcription factor Sall3.
format	article
author	Benyu Liu Buqing Ye Xiaoxiao Zhu Guanling Huang Liuliu Yang Pingping Zhu Ying Du Jiayi Wu Shu Meng Yong Tian Zusen Fan
author_facet	Benyu Liu Buqing Ye Xiaoxiao Zhu Guanling Huang Liuliu Yang Pingping Zhu Ying Du Jiayi Wu Shu Meng Yong Tian Zusen Fan
author_sort	Benyu Liu
title	IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development
title_short	IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development
title_full	IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development
title_fullStr	IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development
title_full_unstemmed	IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development
title_sort	il-7rα glutamylation and activation of transcription factor sall3 promote group 3 ilc development
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/fdcc5a6db53a4add8f579c835b2349d1
work_keys_str_mv	AT benyuliu il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT buqingye il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT xiaoxiaozhu il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT guanlinghuang il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT liuliuyang il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT pingpingzhu il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT yingdu il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT jiayiwu il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT shumeng il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT yongtian il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment AT zusenfan il7raglutamylationandactivationoftranscriptionfactorsall3promotegroup3ilcdevelopment
_version_	1718391703266656256

IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development

Ejemplares similares