Cooperation of Oncolytic Herpes Virotherapy and PD-1 Blockade in Murine Rhabdomyosarcoma Models
Abstract Oncolytic virotherapy is an effective immunotherapeutic approach for cancer treatment via a multistep process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitizing cytokines and promotion of antitumor T cell responses. Solid tumors limit the effectiveness of imm...
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Main Authors: | Chun-Yu Chen, Pin-Yi Wang, Brian Hutzen, Les Sprague, Hayley M. Swain, Julia K. Love, Joseph R. Stanek, Louis Boon, Joe Conner, Timothy P. Cripe |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/fdcd41e11f1d41dba014f2f0f98645df |
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