Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature

Majid Moshirfar,1– 3 Andrew C Thomson,4 William B West Jr,5 MacGregor N Hall,4 Shannon E McCabe,1 Robert J Thomson,4 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual Sci...

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Autores principales: Moshirfar M, Thomson AC, West WB Jr, Hall MN, McCabe SE, Thomson RJ, Ronquillo YC, Hoopes PC
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Publicado: Dove Medical Press 2020
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spelling oai:doaj.org-article:fdcd5f675fbc41adadb238e8efd98df92021-12-02T12:45:27ZInitial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature1177-5483https://doaj.org/article/fdcd5f675fbc41adadb238e8efd98df92020-10-01T00:00:00Zhttps://www.dovepress.com/initial-single-site-experience-using-smile-for-the-treatment-of-astigm-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Majid Moshirfar,1– 3 Andrew C Thomson,4 William B West Jr,5 MacGregor N Hall,4 Shannon E McCabe,1 Robert J Thomson,4 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA; 3Utah Lions Eye Bank, Murray, UT, USA; 4McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, USA; 5University of Utah School of Medicine, Salt Lake City, UT, USACorrespondence: Majid MoshirfarHoopes Vision Research Center, 11820 S. State Street Suite #200, Draper, UT 84020, USATel +1 801-568-0200Fax +1 801-563-0200Email cornea2020@me.comPurpose: To assess a single site’s initial experience with SMILE for the treatment of myopic astigmatism and compare outcomes and vector analysis results with the US Food and Drug Administration (FDA) results and published literature.Patients and Methods: Forty-eight eyes (29 patients) with mean preoperative sphere of − 5.11 ± 1.31 diopters (D) and cylinder of − 1.12 ± 0.60 D underwent SMILE. Visual acuity, refractive, and vector analysis outcomes as well as subjective measures were reported at three and twelve months postoperatively and compared with FDA results and the published literature between 2014 and 2020 involving treatment of patients with mean cylinders of >− 0.50 to ≤− 3.00 D.Results: At three and twelve months, 43 and 32 eyes were evaluated, respectively. At twelve months, mean cylinder power was reduced to − 0.38 ± 0.38 D with 78.1% achieving ≤± 0.50 D. Uncorrected distance visual acuity (UDVA) ≥ 20/20 was achieved in 77.4% of eyes by twelve months with 100% achieving ≥ 20/30 UDVA. No loss of corrected distance visual acuity was observed in eyes seen at twelve months. Correction index (CI) at twelve months was 0.90 indicating overall undercorrection of 10%. Twelve-month CI was 0.96, 0.90, and 0.83 in eyes with preoperative cylinders of <− 1.00 D, ≥− 1.00 to <− 2.00 D, and ≥− 2.00 D, respectively. Mean angle of error was − 1.58 ± 11.61° ranging from − 24.22° to 37.75°.Conclusion: We found SMILE to be an effective and safe means of achieving spectacle independence and improving visual acuity in patients with myopic astigmatism. SMILE has the potential for improved clinical outcomes with better nomogram guidance and advancements in technique. However, surgeons must be aware of the potential for undercorrection in with-the-rule astigmatism and at higher preoperative cylinders and as well as the potential for overcorrection in against-the-rule and lower preoperative cylinder astigmatism.Keywords: SMILE, myopia, astigmatism, vector analysis, ReLEx, toricMoshirfar MThomson ACWest WB JrHall MNMcCabe SEThomson RJRonquillo YCHoopes PCDove Medical Pressarticlesmileastigmatismvector analysisinitial experienceOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3551-3562 (2020)
institution DOAJ
collection DOAJ
language EN
topic smile
astigmatism
vector analysis
initial experience
Ophthalmology
RE1-994
spellingShingle smile
astigmatism
vector analysis
initial experience
Ophthalmology
RE1-994
Moshirfar M
Thomson AC
West WB Jr
Hall MN
McCabe SE
Thomson RJ
Ronquillo YC
Hoopes PC
Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature
description Majid Moshirfar,1– 3 Andrew C Thomson,4 William B West Jr,5 MacGregor N Hall,4 Shannon E McCabe,1 Robert J Thomson,4 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA; 3Utah Lions Eye Bank, Murray, UT, USA; 4McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, USA; 5University of Utah School of Medicine, Salt Lake City, UT, USACorrespondence: Majid MoshirfarHoopes Vision Research Center, 11820 S. State Street Suite #200, Draper, UT 84020, USATel +1 801-568-0200Fax +1 801-563-0200Email cornea2020@me.comPurpose: To assess a single site’s initial experience with SMILE for the treatment of myopic astigmatism and compare outcomes and vector analysis results with the US Food and Drug Administration (FDA) results and published literature.Patients and Methods: Forty-eight eyes (29 patients) with mean preoperative sphere of − 5.11 ± 1.31 diopters (D) and cylinder of − 1.12 ± 0.60 D underwent SMILE. Visual acuity, refractive, and vector analysis outcomes as well as subjective measures were reported at three and twelve months postoperatively and compared with FDA results and the published literature between 2014 and 2020 involving treatment of patients with mean cylinders of >− 0.50 to ≤− 3.00 D.Results: At three and twelve months, 43 and 32 eyes were evaluated, respectively. At twelve months, mean cylinder power was reduced to − 0.38 ± 0.38 D with 78.1% achieving ≤± 0.50 D. Uncorrected distance visual acuity (UDVA) ≥ 20/20 was achieved in 77.4% of eyes by twelve months with 100% achieving ≥ 20/30 UDVA. No loss of corrected distance visual acuity was observed in eyes seen at twelve months. Correction index (CI) at twelve months was 0.90 indicating overall undercorrection of 10%. Twelve-month CI was 0.96, 0.90, and 0.83 in eyes with preoperative cylinders of <− 1.00 D, ≥− 1.00 to <− 2.00 D, and ≥− 2.00 D, respectively. Mean angle of error was − 1.58 ± 11.61° ranging from − 24.22° to 37.75°.Conclusion: We found SMILE to be an effective and safe means of achieving spectacle independence and improving visual acuity in patients with myopic astigmatism. SMILE has the potential for improved clinical outcomes with better nomogram guidance and advancements in technique. However, surgeons must be aware of the potential for undercorrection in with-the-rule astigmatism and at higher preoperative cylinders and as well as the potential for overcorrection in against-the-rule and lower preoperative cylinder astigmatism.Keywords: SMILE, myopia, astigmatism, vector analysis, ReLEx, toric
format article
author Moshirfar M
Thomson AC
West WB Jr
Hall MN
McCabe SE
Thomson RJ
Ronquillo YC
Hoopes PC
author_facet Moshirfar M
Thomson AC
West WB Jr
Hall MN
McCabe SE
Thomson RJ
Ronquillo YC
Hoopes PC
author_sort Moshirfar M
title Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature
title_short Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature
title_full Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature
title_fullStr Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature
title_full_unstemmed Initial Single-Site Experience Using SMILE for the Treatment of Astigmatism in Myopic Eyes and Comparison of Astigmatic Outcomes with Existing Literature
title_sort initial single-site experience using smile for the treatment of astigmatism in myopic eyes and comparison of astigmatic outcomes with existing literature
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/fdcd5f675fbc41adadb238e8efd98df9
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