The rate and molecular spectrum of mutation are selectively maintained in yeast

How natural selection shapes the rate and molecular spectrum of mutations is debated. Yeast mutation accumulation experiments identify a gene promoting mutagenesis and show stabilizing selection maintaining the mutation rate above the drift barrier. Selection also preserves the mutation spectrum.

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Autores principales:	Haoxuan Liu, Jianzhi Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fdcedfe9fd734fdf94a7c009e3c4b18e
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spelling	oai:doaj.org-article:fdcedfe9fd734fdf94a7c009e3c4b18e2021-12-02T18:18:35ZThe rate and molecular spectrum of mutation are selectively maintained in yeast10.1038/s41467-021-24364-62041-1723https://doaj.org/article/fdcedfe9fd734fdf94a7c009e3c4b18e2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24364-6https://doaj.org/toc/2041-1723How natural selection shapes the rate and molecular spectrum of mutations is debated. Yeast mutation accumulation experiments identify a gene promoting mutagenesis and show stabilizing selection maintaining the mutation rate above the drift barrier. Selection also preserves the mutation spectrum.Haoxuan LiuJianzhi ZhangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Haoxuan Liu Jianzhi Zhang The rate and molecular spectrum of mutation are selectively maintained in yeast
description	How natural selection shapes the rate and molecular spectrum of mutations is debated. Yeast mutation accumulation experiments identify a gene promoting mutagenesis and show stabilizing selection maintaining the mutation rate above the drift barrier. Selection also preserves the mutation spectrum.
format	article
author	Haoxuan Liu Jianzhi Zhang
author_facet	Haoxuan Liu Jianzhi Zhang
author_sort	Haoxuan Liu
title	The rate and molecular spectrum of mutation are selectively maintained in yeast
title_short	The rate and molecular spectrum of mutation are selectively maintained in yeast
title_full	The rate and molecular spectrum of mutation are selectively maintained in yeast
title_fullStr	The rate and molecular spectrum of mutation are selectively maintained in yeast
title_full_unstemmed	The rate and molecular spectrum of mutation are selectively maintained in yeast
title_sort	rate and molecular spectrum of mutation are selectively maintained in yeast
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fdcedfe9fd734fdf94a7c009e3c4b18e
work_keys_str_mv	AT haoxuanliu therateandmolecularspectrumofmutationareselectivelymaintainedinyeast AT jianzhizhang therateandmolecularspectrumofmutationareselectivelymaintainedinyeast AT haoxuanliu rateandmolecularspectrumofmutationareselectivelymaintainedinyeast AT jianzhizhang rateandmolecularspectrumofmutationareselectivelymaintainedinyeast
_version_	1718378254012776448

The rate and molecular spectrum of mutation are selectively maintained in yeast

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