The rate and molecular spectrum of mutation are selectively maintained in yeast
How natural selection shapes the rate and molecular spectrum of mutations is debated. Yeast mutation accumulation experiments identify a gene promoting mutagenesis and show stabilizing selection maintaining the mutation rate above the drift barrier. Selection also preserves the mutation spectrum.
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Main Authors: | Haoxuan Liu, Jianzhi Zhang |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/fdcedfe9fd734fdf94a7c009e3c4b18e |
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