The rate and molecular spectrum of mutation are selectively maintained in yeast

How natural selection shapes the rate and molecular spectrum of mutations is debated. Yeast mutation accumulation experiments identify a gene promoting mutagenesis and show stabilizing selection maintaining the mutation rate above the drift barrier. Selection also preserves the mutation spectrum.

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Bibliographic Details
Main Authors: Haoxuan Liu, Jianzhi Zhang
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/fdcedfe9fd734fdf94a7c009e3c4b18e
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