Therapeutic surfactant-stripped frozen micelles

The excipients used to solubilise hydrophobic drugs sometimes interfere with drug behaviour or induce adverse side effects once injected. Here, the authors use a low-temperature process to obtain surfactant-stripped micelles with high drug concentration for delivery of a wide range of hydrophobic ca...

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Autores principales: Yumiao Zhang, Wentao Song, Jumin Geng, Upendra Chitgupi, Hande Unsal, Jasmin Federizon, Javid Rzayev, Dinesh K. Sukumaran, Paschalis Alexandridis, Jonathan F. Lovell
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/fdd78048a2714847872bc42996b6b1e7
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spelling oai:doaj.org-article:fdd78048a2714847872bc42996b6b1e72021-12-02T15:34:53ZTherapeutic surfactant-stripped frozen micelles10.1038/ncomms116492041-1723https://doaj.org/article/fdd78048a2714847872bc42996b6b1e72016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11649https://doaj.org/toc/2041-1723The excipients used to solubilise hydrophobic drugs sometimes interfere with drug behaviour or induce adverse side effects once injected. Here, the authors use a low-temperature process to obtain surfactant-stripped micelles with high drug concentration for delivery of a wide range of hydrophobic cargoes.Yumiao ZhangWentao SongJumin GengUpendra ChitgupiHande UnsalJasmin FederizonJavid RzayevDinesh K. SukumaranPaschalis AlexandridisJonathan F. LovellNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yumiao Zhang
Wentao Song
Jumin Geng
Upendra Chitgupi
Hande Unsal
Jasmin Federizon
Javid Rzayev
Dinesh K. Sukumaran
Paschalis Alexandridis
Jonathan F. Lovell
Therapeutic surfactant-stripped frozen micelles
description The excipients used to solubilise hydrophobic drugs sometimes interfere with drug behaviour or induce adverse side effects once injected. Here, the authors use a low-temperature process to obtain surfactant-stripped micelles with high drug concentration for delivery of a wide range of hydrophobic cargoes.
format article
author Yumiao Zhang
Wentao Song
Jumin Geng
Upendra Chitgupi
Hande Unsal
Jasmin Federizon
Javid Rzayev
Dinesh K. Sukumaran
Paschalis Alexandridis
Jonathan F. Lovell
author_facet Yumiao Zhang
Wentao Song
Jumin Geng
Upendra Chitgupi
Hande Unsal
Jasmin Federizon
Javid Rzayev
Dinesh K. Sukumaran
Paschalis Alexandridis
Jonathan F. Lovell
author_sort Yumiao Zhang
title Therapeutic surfactant-stripped frozen micelles
title_short Therapeutic surfactant-stripped frozen micelles
title_full Therapeutic surfactant-stripped frozen micelles
title_fullStr Therapeutic surfactant-stripped frozen micelles
title_full_unstemmed Therapeutic surfactant-stripped frozen micelles
title_sort therapeutic surfactant-stripped frozen micelles
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/fdd78048a2714847872bc42996b6b1e7
work_keys_str_mv AT yumiaozhang therapeuticsurfactantstrippedfrozenmicelles
AT wentaosong therapeuticsurfactantstrippedfrozenmicelles
AT jumingeng therapeuticsurfactantstrippedfrozenmicelles
AT upendrachitgupi therapeuticsurfactantstrippedfrozenmicelles
AT handeunsal therapeuticsurfactantstrippedfrozenmicelles
AT jasminfederizon therapeuticsurfactantstrippedfrozenmicelles
AT javidrzayev therapeuticsurfactantstrippedfrozenmicelles
AT dineshksukumaran therapeuticsurfactantstrippedfrozenmicelles
AT paschalisalexandridis therapeuticsurfactantstrippedfrozenmicelles
AT jonathanflovell therapeuticsurfactantstrippedfrozenmicelles
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