The Use of Inhibitors of Tyrosine Kinase in Paediatric Haemato-Oncology—When and Why?
The fundamental pathophysiology of malignancies is dysregulation of the signalling pathways. Protein tyrosine kinases (PTKs) are among the enzymes which, if mutated, play a critical role in carcinogenesis. The best-studied rearrangement, which enhances PTK activity and causes atypical proliferation,...
Guardado en:
Autores principales: | Agnieszka Kaczmarska, Patrycja Śliwa, Monika Lejman, Joanna Zawitkowska |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/fddfddc3f7d44f13a4fee49601feba77 |
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