Retrobulbar Fibrosarcoma in a Sheep

This report describes a case of a retrobulbar fibrosarcoma in a 4-year-old female sheep. A big tumor was protruding from the orbit but not invading the surrounding tissue and was easily removed surgically. The grayish colored mass was 19×13×8 cm in size and hard. The surface of the tumor was irregul...

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Autores principales:	Ozmen Ozlem, Sirin Sengoz Ozlem, Çinar Harun, Dolu Hüseyin
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2016
Materias:	retrobulbar fibrosarcoma histopathology immunohistochemistry sheep Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/fde83da574974462bf439eb4985b845d
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spelling	oai:doaj.org-article:fde83da574974462bf439eb4985b845d2021-11-17T21:27:51ZRetrobulbar Fibrosarcoma in a Sheep1820-744810.1515/acve-2016-0023https://doaj.org/article/fde83da574974462bf439eb4985b845d2016-06-01T00:00:00Zhttps://doi.org/10.1515/acve-2016-0023https://doaj.org/toc/1820-7448This report describes a case of a retrobulbar fibrosarcoma in a 4-year-old female sheep. A big tumor was protruding from the orbit but not invading the surrounding tissue and was easily removed surgically. The grayish colored mass was 19×13×8 cm in size and hard. The surface of the tumor was irregular and ulcerated. Marked hemorrhage and necrotic areas were present across the whitish cut surface. Histopathologically, the mass was composed of spindle shaped, anaplastic pleomorphic cells. Masson’s trichrome staining revealed a collagenous matrix in the tissue. Immunohistochemically, the mass was positive for vimentin and proliferating cell nuclear antigen but negative for smooth muscle actin, desmin, glial fibrilar acidic protein and S100 protein antibodies. According to histopathological and immunohistochemical findings the tumor was diagnosed as fibrosarcoma. To the authors’ knowledge, this is the first report of ocular fibrosarcoma in a sheep.Ozmen OzlemSirin Sengoz OzlemÇinar HarunDolu HüseyinSciendoarticleretrobulbar fibrosarcomahistopathologyimmunohistochemistrysheepVeterinary medicineSF600-1100ENActa Veterinaria, Vol 66, Iss 2, Pp 265-270 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	retrobulbar fibrosarcoma histopathology immunohistochemistry sheep Veterinary medicine SF600-1100
spellingShingle	retrobulbar fibrosarcoma histopathology immunohistochemistry sheep Veterinary medicine SF600-1100 Ozmen Ozlem Sirin Sengoz Ozlem Çinar Harun Dolu Hüseyin Retrobulbar Fibrosarcoma in a Sheep
description	This report describes a case of a retrobulbar fibrosarcoma in a 4-year-old female sheep. A big tumor was protruding from the orbit but not invading the surrounding tissue and was easily removed surgically. The grayish colored mass was 19×13×8 cm in size and hard. The surface of the tumor was irregular and ulcerated. Marked hemorrhage and necrotic areas were present across the whitish cut surface. Histopathologically, the mass was composed of spindle shaped, anaplastic pleomorphic cells. Masson’s trichrome staining revealed a collagenous matrix in the tissue. Immunohistochemically, the mass was positive for vimentin and proliferating cell nuclear antigen but negative for smooth muscle actin, desmin, glial fibrilar acidic protein and S100 protein antibodies. According to histopathological and immunohistochemical findings the tumor was diagnosed as fibrosarcoma. To the authors’ knowledge, this is the first report of ocular fibrosarcoma in a sheep.
format	article
author	Ozmen Ozlem Sirin Sengoz Ozlem Çinar Harun Dolu Hüseyin
author_facet	Ozmen Ozlem Sirin Sengoz Ozlem Çinar Harun Dolu Hüseyin
author_sort	Ozmen Ozlem
title	Retrobulbar Fibrosarcoma in a Sheep
title_short	Retrobulbar Fibrosarcoma in a Sheep
title_full	Retrobulbar Fibrosarcoma in a Sheep
title_fullStr	Retrobulbar Fibrosarcoma in a Sheep
title_full_unstemmed	Retrobulbar Fibrosarcoma in a Sheep
title_sort	retrobulbar fibrosarcoma in a sheep
publisher	Sciendo
publishDate	2016
url	https://doaj.org/article/fde83da574974462bf439eb4985b845d
work_keys_str_mv	AT ozmenozlem retrobulbarfibrosarcomainasheep AT sirinsengozozlem retrobulbarfibrosarcomainasheep AT cinarharun retrobulbarfibrosarcomainasheep AT doluhuseyin retrobulbarfibrosarcomainasheep
_version_	1718425329858510848

Retrobulbar Fibrosarcoma in a Sheep

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