The current research status of normal tension glaucoma

Xue-Song Mi,1,2 Ti-Fei Yuan,3,4 Kwok-Fai So2,4,5 1Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, People’s Republic of China; 2Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, People’s Repu...

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Autores principales:	Mi XS, Yuan TF, So KF
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	normal tension glaucoma neurovascular unit degeneration neuroprotection; Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/fdee87b573824d48a3c7a3e712f7f509
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spelling	oai:doaj.org-article:fdee87b573824d48a3c7a3e712f7f5092021-12-02T00:09:48ZThe current research status of normal tension glaucoma1178-1998https://doaj.org/article/fdee87b573824d48a3c7a3e712f7f5092014-09-01T00:00:00Zhttps://www.dovepress.com/the-current-research-status-of-normal-tension-glaucoma-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Xue-Song Mi,1,2 Ti-Fei Yuan,3,4 Kwok-Fai So2,4,5 1Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, People’s Republic of China; 2Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, People’s Republic of China; 3School of Psychology, Nanjing Normal University, Nanjing, People’s Republic of China; 4Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, People’s Republic of China; 5GHM Institute of CNS Regeneration, Jinan University, Guangzhou, People’s Republic of China Abstract: Normal tension glaucoma (NTG) is a progressive optic neuropathy that mimics primary open-angle glaucoma, but lacks the findings of elevated intraocular pressure or other mitigating factors that can lead to optic neuropathy. The present review summarized the causes, genetics, and mechanisms underlying NTG in both animal models and human patients. We also proposed that the neurovascular unit is a therapeutic target for NTG management. Keywords: aging, genetics, neurovascular unit, primary open-angle glaucoma, treatmentMi XSYuan TFSo KFDove Medical Pressarticlenormal tension glaucomaneurovascular unitdegenerationneuroprotection;GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1563-1571 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	normal tension glaucoma neurovascular unit degeneration neuroprotection; Geriatrics RC952-954.6
spellingShingle	normal tension glaucoma neurovascular unit degeneration neuroprotection; Geriatrics RC952-954.6 Mi XS Yuan TF So KF The current research status of normal tension glaucoma
description	Xue-Song Mi,1,2 Ti-Fei Yuan,3,4 Kwok-Fai So2,4,5 1Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, People’s Republic of China; 2Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, People’s Republic of China; 3School of Psychology, Nanjing Normal University, Nanjing, People’s Republic of China; 4Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, People’s Republic of China; 5GHM Institute of CNS Regeneration, Jinan University, Guangzhou, People’s Republic of China Abstract: Normal tension glaucoma (NTG) is a progressive optic neuropathy that mimics primary open-angle glaucoma, but lacks the findings of elevated intraocular pressure or other mitigating factors that can lead to optic neuropathy. The present review summarized the causes, genetics, and mechanisms underlying NTG in both animal models and human patients. We also proposed that the neurovascular unit is a therapeutic target for NTG management. Keywords: aging, genetics, neurovascular unit, primary open-angle glaucoma, treatment
format	article
author	Mi XS Yuan TF So KF
author_facet	Mi XS Yuan TF So KF
author_sort	Mi XS
title	The current research status of normal tension glaucoma
title_short	The current research status of normal tension glaucoma
title_full	The current research status of normal tension glaucoma
title_fullStr	The current research status of normal tension glaucoma
title_full_unstemmed	The current research status of normal tension glaucoma
title_sort	current research status of normal tension glaucoma
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/fdee87b573824d48a3c7a3e712f7f509
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The current research status of normal tension glaucoma

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