Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules

Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules

Ciliary beating is mediated by the axonemal central pair microtubules, though how these non-centrosomal microtubules form is poorly understood. Here the authors show that a trio of proteins act cooperatively to initiate central microtubule formation in mammals.

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Autores principales: Hao Liu, Jianqun Zheng, Lei Zhu, Lele Xie, Yawen Chen, Yirong Zhang, Wei Zhang, Yue Yin, Chao Peng, Jun Zhou, Xueliang Zhu, Xiumin Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fdf69f04d6aa4ff1bf5f7802f81d420e
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spelling oai:doaj.org-article:fdf69f04d6aa4ff1bf5f7802f81d420e2021-12-02T19:16:20ZWdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules10.1038/s41467-021-26058-52041-1723https://doaj.org/article/fdf69f04d6aa4ff1bf5f7802f81d420e2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26058-5https://doaj.org/toc/2041-1723Ciliary beating is mediated by the axonemal central pair microtubules, though how these non-centrosomal microtubules form is poorly understood. Here the authors show that a trio of proteins act cooperatively to initiate central microtubule formation in mammals.Hao LiuJianqun ZhengLei ZhuLele XieYawen ChenYirong ZhangWei ZhangYue YinChao PengJun ZhouXueliang ZhuXiumin YanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hao Liu
Jianqun Zheng
Lei Zhu
Lele Xie
Yawen Chen
Yirong Zhang
Wei Zhang
Yue Yin
Chao Peng
Jun Zhou
Xueliang Zhu
Xiumin Yan
Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules
description Ciliary beating is mediated by the axonemal central pair microtubules, though how these non-centrosomal microtubules form is poorly understood. Here the authors show that a trio of proteins act cooperatively to initiate central microtubule formation in mammals.
format article
author Hao Liu
Jianqun Zheng
Lei Zhu
Lele Xie
Yawen Chen
Yirong Zhang
Wei Zhang
Yue Yin
Chao Peng
Jun Zhou
Xueliang Zhu
Xiumin Yan
author_facet Hao Liu
Jianqun Zheng
Lei Zhu
Lele Xie
Yawen Chen
Yirong Zhang
Wei Zhang
Yue Yin
Chao Peng
Jun Zhou
Xueliang Zhu
Xiumin Yan
author_sort Hao Liu
title Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules
title_short Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules
title_full Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules
title_fullStr Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules
title_full_unstemmed Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules
title_sort wdr47, camsaps, and katanin cooperate to generate ciliary central microtubules
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/fdf69f04d6aa4ff1bf5f7802f81d420e
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AT leizhu wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT lelexie wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT yawenchen wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT yirongzhang wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT weizhang wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT yueyin wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT chaopeng wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT junzhou wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT xueliangzhu wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
AT xiuminyan wdr47camsapsandkatanincooperatetogenerateciliarycentralmicrotubules
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