The Antagonism of Corticotropin-Releasing Factor Receptor-1 in Brain Suppress Stress-Induced Propofol Self-Administration in Rats

Propofol addiction has been detected in humans and rats, which may be facilitated by stress. Corticotropin-releasing factor acts through the corticotropin-releasing factor (CRF) receptor-1 (CRF1R) and CRF2 receptor-2 (CRF2R) and is a crucial candidate target for the interaction between stress and dr...

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Autores principales: Zhanglei Dong, Gaolong Zhang, Saiqiong Xiang, Chenchen Jiang, Zhichuan Chen, Yan Li, Bingwu Huang, Wenhua Zhou, Qingquan Lian, Binbin Wu
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/fdf7d1f5f94b4d34aa735f339c3d575c
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