Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast

Metaphase cells preferentially promote actin cable assembly through cyclin-dependent kinase 1 (Cdk1) activity. Here the authors identify fimbrin as one of the main metaphase Cdk1 targets for cell cycle regulation of actin cable assembly in budding yeast.

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Auteurs principaux: Yansong Miao, Xuemei Han, Liangzhen Zheng, Ying Xie, Yuguang Mu, John R. Yates, David G. Drubin
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/fdfca46289664a5986ba5b942b6e5a6a
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Résumé:Metaphase cells preferentially promote actin cable assembly through cyclin-dependent kinase 1 (Cdk1) activity. Here the authors identify fimbrin as one of the main metaphase Cdk1 targets for cell cycle regulation of actin cable assembly in budding yeast.