Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
The molecular identity of renal glomerular cells is poorly characterized and rodent glomerulopathy models translate poorly to humans. Here, the authors show molecular signatures of glomerulus-associated cells using single cell RNA sequencing and highlight differences between mouse and human cells.
Guardado en:
Autores principales: | Bing He, Ping Chen, Sonia Zambrano, Dina Dabaghie, Yizhou Hu, Katja Möller-Hackbarth, David Unnersjö-Jess, Gül Gizem Korkut, Emmanuelle Charrin, Marie Jeansson, Maria Bintanel-Morcillo, Anna Witasp, Lars Wennberg, Annika Wernerson, Bernhard Schermer, Thomas Benzing, Patrik Ernfors, Christer Betsholtz, Mark Lal, Rickard Sandberg, Jaakko Patrakka |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/fe04160ada134a20a0af7aef65e1f106 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice
por: Weizu Li, et al.
Publicado: (2017) -
Targeted delivery of celastrol to mesangial cells is effective against mesangioproliferative glomerulonephritis
por: Ling Guo, et al.
Publicado: (2017) -
Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells
por: Shigeyoshi Oba, et al.
Publicado: (2018) -
Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression
por: Yuehong Ma, et al.
Publicado: (2021) -
Shenhua Tablet inhibits mesangial cell proliferation in rats with chronic anti-Thy-1 nephritis
por: Geng,Wenjia, et al.
Publicado: (2016)