Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection

Human bocavirus 1 (HBoV1), a common pediatric respiratory pathogen, can persist in airway secretions for months hampering diagnosis. It also persists in tonsils, providing potential reservoirs for airway shedding, with the exact location, host cell types, and virus activity unknown.

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Autores principales: Man Xu, Maria Fernanda Perdomo, Salla Mattola, Lari Pyöriä, Mari Toppinen, Jianming Qiu, Maija Vihinen-Ranta, Klaus Hedman, Johanna Nokso-Koivisto, Leena-Maija Aaltonen, Maria Söderlund-Venermo
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/fe108de5e10844ae9182f0124f92a550
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spelling oai:doaj.org-article:fe108de5e10844ae9182f0124f92a5502021-11-03T18:15:37ZPersistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection2161-21292150-751110.1128/mBio.03132-20https://doaj.org/article/fe108de5e10844ae9182f0124f92a5502021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03132-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Human bocavirus 1 (HBoV1), a common pediatric respiratory pathogen, can persist in airway secretions for months hampering diagnosis. It also persists in tonsils, providing potential reservoirs for airway shedding, with the exact location, host cell types, and virus activity unknown.Man XuMaria Fernanda PerdomoSalla MattolaLari PyöriäMari ToppinenJianming QiuMaija Vihinen-RantaKlaus HedmanJohanna Nokso-KoivistoLeena-Maija AaltonenMaria Söderlund-VenermoAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Man Xu
Maria Fernanda Perdomo
Salla Mattola
Lari Pyöriä
Mari Toppinen
Jianming Qiu
Maija Vihinen-Ranta
Klaus Hedman
Johanna Nokso-Koivisto
Leena-Maija Aaltonen
Maria Söderlund-Venermo
Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection
description Human bocavirus 1 (HBoV1), a common pediatric respiratory pathogen, can persist in airway secretions for months hampering diagnosis. It also persists in tonsils, providing potential reservoirs for airway shedding, with the exact location, host cell types, and virus activity unknown.
format article
author Man Xu
Maria Fernanda Perdomo
Salla Mattola
Lari Pyöriä
Mari Toppinen
Jianming Qiu
Maija Vihinen-Ranta
Klaus Hedman
Johanna Nokso-Koivisto
Leena-Maija Aaltonen
Maria Söderlund-Venermo
author_facet Man Xu
Maria Fernanda Perdomo
Salla Mattola
Lari Pyöriä
Mari Toppinen
Jianming Qiu
Maija Vihinen-Ranta
Klaus Hedman
Johanna Nokso-Koivisto
Leena-Maija Aaltonen
Maria Söderlund-Venermo
author_sort Man Xu
title Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection
title_short Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection
title_full Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection
title_fullStr Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection
title_full_unstemmed Persistence of Human Bocavirus 1 in Tonsillar Germinal Centers and Antibody-Dependent Enhancement of Infection
title_sort persistence of human bocavirus 1 in tonsillar germinal centers and antibody-dependent enhancement of infection
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/fe108de5e10844ae9182f0124f92a550
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