Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid

DNA is an attractive nanomaterial, yet limited compared to polyamides due to low stability and mechanical issues. Here, the authors combine polyamide and DNA characteristics to form mechanically rigid self-assembled peptide nucleic acid based materials with high stiffness and Young’s modulus.

Guardado en:
Detalles Bibliográficos
Autores principales: Vasantha Basavalingappa, Santu Bera, Bin Xue, Ido Azuri, Yiming Tang, Kai Tao, Linda J. W. Shimon, Michael R. Sawaya, Sofiya Kolusheva, David S. Eisenberg, Leeor Kronik, Yi Cao, Guanghong Wei, Ehud Gazit
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/fe1796cb54ed4a099a3b5e137059ad29
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:fe1796cb54ed4a099a3b5e137059ad29
record_format dspace
spelling oai:doaj.org-article:fe1796cb54ed4a099a3b5e137059ad292021-12-02T14:40:17ZMechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid10.1038/s41467-019-13250-x2041-1723https://doaj.org/article/fe1796cb54ed4a099a3b5e137059ad292019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13250-xhttps://doaj.org/toc/2041-1723DNA is an attractive nanomaterial, yet limited compared to polyamides due to low stability and mechanical issues. Here, the authors combine polyamide and DNA characteristics to form mechanically rigid self-assembled peptide nucleic acid based materials with high stiffness and Young’s modulus.Vasantha BasavalingappaSantu BeraBin XueIdo AzuriYiming TangKai TaoLinda J. W. ShimonMichael R. SawayaSofiya KolushevaDavid S. EisenbergLeeor KronikYi CaoGuanghong WeiEhud GazitNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vasantha Basavalingappa
Santu Bera
Bin Xue
Ido Azuri
Yiming Tang
Kai Tao
Linda J. W. Shimon
Michael R. Sawaya
Sofiya Kolusheva
David S. Eisenberg
Leeor Kronik
Yi Cao
Guanghong Wei
Ehud Gazit
Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
description DNA is an attractive nanomaterial, yet limited compared to polyamides due to low stability and mechanical issues. Here, the authors combine polyamide and DNA characteristics to form mechanically rigid self-assembled peptide nucleic acid based materials with high stiffness and Young’s modulus.
format article
author Vasantha Basavalingappa
Santu Bera
Bin Xue
Ido Azuri
Yiming Tang
Kai Tao
Linda J. W. Shimon
Michael R. Sawaya
Sofiya Kolusheva
David S. Eisenberg
Leeor Kronik
Yi Cao
Guanghong Wei
Ehud Gazit
author_facet Vasantha Basavalingappa
Santu Bera
Bin Xue
Ido Azuri
Yiming Tang
Kai Tao
Linda J. W. Shimon
Michael R. Sawaya
Sofiya Kolusheva
David S. Eisenberg
Leeor Kronik
Yi Cao
Guanghong Wei
Ehud Gazit
author_sort Vasantha Basavalingappa
title Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
title_short Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
title_full Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
title_fullStr Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
title_full_unstemmed Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
title_sort mechanically rigid supramolecular assemblies formed from an fmoc-guanine conjugated peptide nucleic acid
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/fe1796cb54ed4a099a3b5e137059ad29
work_keys_str_mv AT vasanthabasavalingappa mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT santubera mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT binxue mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT idoazuri mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT yimingtang mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT kaitao mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT lindajwshimon mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT michaelrsawaya mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT sofiyakolusheva mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT davidseisenberg mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT leeorkronik mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT yicao mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT guanghongwei mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
AT ehudgazit mechanicallyrigidsupramolecularassembliesformedfromanfmocguanineconjugatedpeptidenucleicacid
_version_ 1718390394663731200