Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing

A chromosome is composed of structurally and functionally distinct domains. Here, Tashiro et al. report that the conserved centromeric protein Sgo2 localizes at the subtelomeres preferentially during G2phase and is essential for the formation of a highly condensed subtelomeric chromatin body “knob”....

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Autores principales:	Sanki Tashiro, Tetsuya Handa, Atsushi Matsuda, Takuto Ban, Toru Takigawa, Kazumi Miyasato, Kojiro Ishii, Kazuto Kugou, Kunihiro Ohta, Yasushi Hiraoka, Hisao Masukata, Junko Kanoh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fe18f516242748168003ebe110edff16
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spelling	oai:doaj.org-article:fe18f516242748168003ebe110edff162021-12-02T14:39:53ZShugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing10.1038/ncomms103932041-1723https://doaj.org/article/fe18f516242748168003ebe110edff162016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10393https://doaj.org/toc/2041-1723A chromosome is composed of structurally and functionally distinct domains. Here, Tashiro et al. report that the conserved centromeric protein Sgo2 localizes at the subtelomeres preferentially during G2phase and is essential for the formation of a highly condensed subtelomeric chromatin body “knob”.Sanki TashiroTetsuya HandaAtsushi MatsudaTakuto BanToru TakigawaKazumi MiyasatoKojiro IshiiKazuto KugouKunihiro OhtaYasushi HiraokaHisao MasukataJunko KanohNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sanki Tashiro Tetsuya Handa Atsushi Matsuda Takuto Ban Toru Takigawa Kazumi Miyasato Kojiro Ishii Kazuto Kugou Kunihiro Ohta Yasushi Hiraoka Hisao Masukata Junko Kanoh Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
description	A chromosome is composed of structurally and functionally distinct domains. Here, Tashiro et al. report that the conserved centromeric protein Sgo2 localizes at the subtelomeres preferentially during G2phase and is essential for the formation of a highly condensed subtelomeric chromatin body “knob”.
format	article
author	Sanki Tashiro Tetsuya Handa Atsushi Matsuda Takuto Ban Toru Takigawa Kazumi Miyasato Kojiro Ishii Kazuto Kugou Kunihiro Ohta Yasushi Hiraoka Hisao Masukata Junko Kanoh
author_facet	Sanki Tashiro Tetsuya Handa Atsushi Matsuda Takuto Ban Toru Takigawa Kazumi Miyasato Kojiro Ishii Kazuto Kugou Kunihiro Ohta Yasushi Hiraoka Hisao Masukata Junko Kanoh
author_sort	Sanki Tashiro
title	Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
title_short	Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
title_full	Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
title_fullStr	Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
title_full_unstemmed	Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
title_sort	shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/fe18f516242748168003ebe110edff16
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Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing

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