Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing
A chromosome is composed of structurally and functionally distinct domains. Here, Tashiro et al. report that the conserved centromeric protein Sgo2 localizes at the subtelomeres preferentially during G2phase and is essential for the formation of a highly condensed subtelomeric chromatin body “knob”....
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Autores principales: | Sanki Tashiro, Tetsuya Handa, Atsushi Matsuda, Takuto Ban, Toru Takigawa, Kazumi Miyasato, Kojiro Ishii, Kazuto Kugou, Kunihiro Ohta, Yasushi Hiraoka, Hisao Masukata, Junko Kanoh |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/fe18f516242748168003ebe110edff16 |
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