Skeletal muscle transcriptome in healthy aging

As human skeletal muscle ages, gene expression programs change and reflect damage accumulation and homeostatic resilience mechanisms. Here, the authors present a detailed framework of the global transcriptome that characterizes skeletal muscle during aging in healthy individuals.

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Autores principales: Robert A. Tumasian, Abhinav Harish, Gautam Kundu, Jen-Hao Yang, Ceereena Ubaida-Mohien, Marta Gonzalez-Freire, Mary Kaileh, Linda M. Zukley, Chee W. Chia, Alexey Lyashkov, William H. Wood, Yulan Piao, Christopher Coletta, Jun Ding, Myriam Gorospe, Ranjan Sen, Supriyo De, Luigi Ferrucci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fe1b133469394d2ea2f9de8c7479f7a6
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spelling oai:doaj.org-article:fe1b133469394d2ea2f9de8c7479f7a62021-12-02T13:26:23ZSkeletal muscle transcriptome in healthy aging10.1038/s41467-021-22168-22041-1723https://doaj.org/article/fe1b133469394d2ea2f9de8c7479f7a62021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22168-2https://doaj.org/toc/2041-1723As human skeletal muscle ages, gene expression programs change and reflect damage accumulation and homeostatic resilience mechanisms. Here, the authors present a detailed framework of the global transcriptome that characterizes skeletal muscle during aging in healthy individuals.Robert A. TumasianAbhinav HarishGautam KunduJen-Hao YangCeereena Ubaida-MohienMarta Gonzalez-FreireMary KailehLinda M. ZukleyChee W. ChiaAlexey LyashkovWilliam H. WoodYulan PiaoChristopher ColettaJun DingMyriam GorospeRanjan SenSupriyo DeLuigi FerrucciNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Robert A. Tumasian
Abhinav Harish
Gautam Kundu
Jen-Hao Yang
Ceereena Ubaida-Mohien
Marta Gonzalez-Freire
Mary Kaileh
Linda M. Zukley
Chee W. Chia
Alexey Lyashkov
William H. Wood
Yulan Piao
Christopher Coletta
Jun Ding
Myriam Gorospe
Ranjan Sen
Supriyo De
Luigi Ferrucci
Skeletal muscle transcriptome in healthy aging
description As human skeletal muscle ages, gene expression programs change and reflect damage accumulation and homeostatic resilience mechanisms. Here, the authors present a detailed framework of the global transcriptome that characterizes skeletal muscle during aging in healthy individuals.
format article
author Robert A. Tumasian
Abhinav Harish
Gautam Kundu
Jen-Hao Yang
Ceereena Ubaida-Mohien
Marta Gonzalez-Freire
Mary Kaileh
Linda M. Zukley
Chee W. Chia
Alexey Lyashkov
William H. Wood
Yulan Piao
Christopher Coletta
Jun Ding
Myriam Gorospe
Ranjan Sen
Supriyo De
Luigi Ferrucci
author_facet Robert A. Tumasian
Abhinav Harish
Gautam Kundu
Jen-Hao Yang
Ceereena Ubaida-Mohien
Marta Gonzalez-Freire
Mary Kaileh
Linda M. Zukley
Chee W. Chia
Alexey Lyashkov
William H. Wood
Yulan Piao
Christopher Coletta
Jun Ding
Myriam Gorospe
Ranjan Sen
Supriyo De
Luigi Ferrucci
author_sort Robert A. Tumasian
title Skeletal muscle transcriptome in healthy aging
title_short Skeletal muscle transcriptome in healthy aging
title_full Skeletal muscle transcriptome in healthy aging
title_fullStr Skeletal muscle transcriptome in healthy aging
title_full_unstemmed Skeletal muscle transcriptome in healthy aging
title_sort skeletal muscle transcriptome in healthy aging
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/fe1b133469394d2ea2f9de8c7479f7a6
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