Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6

Abstract Growth failure in cystic fibrosis (CF) patients has been well-documented and shown to correlate with poorer disease outcomes. This observation is also true in CF animal models, including mouse, pig, rat, and ferret. The etiology underlying growth deficits is unknown, and our previous work d...

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Autores principales: Sharon M. Rymut, Deborah A. Corey, Dana M. Valerio, Bernadette O. Erokwu, Chris A. Flask, Thomas J. Kelley, Craig A. Hodges
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/fe1f349f88014e678cceaef9c8ae403c
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