Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

The identification and characterisation of dormant cells is currently difficult. Here the authors report Optical Stem Cell Activity Reporter (OSCAR) to assess RNA polymerase II activity and identify dormant cell populations in intestinal epithelial cells in vivo.

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Autores principales:	Rasmus Freter, Paola Falletta, Omid Omrani, Mahdi Rasa, Katharine Herbert, Francesco Annunziata, Alberto Minetti, Anna Krepelova, Lisa Adam, Sandra Käppel, Tina Rüdiger, Zhao-Qi Wang, Colin R. Goding, Francesco Neri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fe29dc36efb94fd6a94dead8d21a2d0f
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spelling	oai:doaj.org-article:fe29dc36efb94fd6a94dead8d21a2d0f2021-12-02T18:24:58ZEstablishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells10.1038/s41467-021-23580-42041-1723https://doaj.org/article/fe29dc36efb94fd6a94dead8d21a2d0f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23580-4https://doaj.org/toc/2041-1723The identification and characterisation of dormant cells is currently difficult. Here the authors report Optical Stem Cell Activity Reporter (OSCAR) to assess RNA polymerase II activity and identify dormant cell populations in intestinal epithelial cells in vivo.Rasmus FreterPaola FallettaOmid OmraniMahdi RasaKatharine HerbertFrancesco AnnunziataAlberto MinettiAnna KrepelovaLisa AdamSandra KäppelTina RüdigerZhao-Qi WangColin R. GodingFrancesco NeriNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rasmus Freter Paola Falletta Omid Omrani Mahdi Rasa Katharine Herbert Francesco Annunziata Alberto Minetti Anna Krepelova Lisa Adam Sandra Käppel Tina Rüdiger Zhao-Qi Wang Colin R. Goding Francesco Neri Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
description	The identification and characterisation of dormant cells is currently difficult. Here the authors report Optical Stem Cell Activity Reporter (OSCAR) to assess RNA polymerase II activity and identify dormant cell populations in intestinal epithelial cells in vivo.
format	article
author	Rasmus Freter Paola Falletta Omid Omrani Mahdi Rasa Katharine Herbert Francesco Annunziata Alberto Minetti Anna Krepelova Lisa Adam Sandra Käppel Tina Rüdiger Zhao-Qi Wang Colin R. Goding Francesco Neri
author_facet	Rasmus Freter Paola Falletta Omid Omrani Mahdi Rasa Katharine Herbert Francesco Annunziata Alberto Minetti Anna Krepelova Lisa Adam Sandra Käppel Tina Rüdiger Zhao-Qi Wang Colin R. Goding Francesco Neri
author_sort	Rasmus Freter
title	Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
title_short	Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
title_full	Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
title_fullStr	Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
title_full_unstemmed	Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
title_sort	establishment of a fluorescent reporter of rna-polymerase ii activity to identify dormant cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fe29dc36efb94fd6a94dead8d21a2d0f
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Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

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