A mechanistic model of early FcεRI signaling: lipid rafts and the question of protection from dephosphorylation.

We present a model of the early events in mast cell signaling mediated by FcεRI where the plasma membrane is composed of many small ordered lipid domains (rafts), surrounded by a non-order region of lipids consisting of the remaining plasma membrane. The model treats the rafts as transient structure...

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Bibliographic Details
Main Authors: Dipak Barua, Byron Goldstein
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/fe30ebf58f004bd8b0eb894bc3d89ab4
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