A viral load-based model for epidemic spread on spatial networks

In this paper, we propose a Boltzmann-type kinetic model of the spreading of an infectious disease on a network. The latter describes the connections among countries, cities or districts depending on the spatial scale of interest. The disease transmission is represented in terms of the viral load of...

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Autores principales: Nadia Loy, Andrea Tosin
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Lenguaje:EN
Publicado: AIMS Press 2021
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Acceso en línea:https://doaj.org/article/fe33b47190524aca9ef70be5e596729a
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spelling oai:doaj.org-article:fe33b47190524aca9ef70be5e596729a2021-11-09T02:34:12ZA viral load-based model for epidemic spread on spatial networks10.3934/mbe.20212851551-0018https://doaj.org/article/fe33b47190524aca9ef70be5e596729a2021-06-01T00:00:00Zhttps://www.aimspress.com/article/doi/10.3934/mbe.2021285?viewType=HTMLhttps://doaj.org/toc/1551-0018In this paper, we propose a Boltzmann-type kinetic model of the spreading of an infectious disease on a network. The latter describes the connections among countries, cities or districts depending on the spatial scale of interest. The disease transmission is represented in terms of the viral load of the individuals and is mediated by social contacts among them, taking into account their displacements across the nodes of the network. We formally derive the hydrodynamic equations for the density and the mean viral load of the individuals on the network and we analyse the large-time trends of these quantities with special emphasis on the cases of blow-up or eradication of the infection. By means of numerical tests, we also investigate the impact of confinement measures, such as quarantine or localised lockdown, on the diffusion of the disease on the network.Nadia LoyAndrea TosinAIMS Pressarticleboltzmann-type equationsmarkov-type jump processeslabel switchingcommutersquarantineBiotechnologyTP248.13-248.65MathematicsQA1-939ENMathematical Biosciences and Engineering, Vol 18, Iss 5, Pp 5635-5663 (2021)
institution DOAJ
collection DOAJ
language EN
topic boltzmann-type equations
markov-type jump processes
label switching
commuters
quarantine
Biotechnology
TP248.13-248.65
Mathematics
QA1-939
spellingShingle boltzmann-type equations
markov-type jump processes
label switching
commuters
quarantine
Biotechnology
TP248.13-248.65
Mathematics
QA1-939
Nadia Loy
Andrea Tosin
A viral load-based model for epidemic spread on spatial networks
description In this paper, we propose a Boltzmann-type kinetic model of the spreading of an infectious disease on a network. The latter describes the connections among countries, cities or districts depending on the spatial scale of interest. The disease transmission is represented in terms of the viral load of the individuals and is mediated by social contacts among them, taking into account their displacements across the nodes of the network. We formally derive the hydrodynamic equations for the density and the mean viral load of the individuals on the network and we analyse the large-time trends of these quantities with special emphasis on the cases of blow-up or eradication of the infection. By means of numerical tests, we also investigate the impact of confinement measures, such as quarantine or localised lockdown, on the diffusion of the disease on the network.
format article
author Nadia Loy
Andrea Tosin
author_facet Nadia Loy
Andrea Tosin
author_sort Nadia Loy
title A viral load-based model for epidemic spread on spatial networks
title_short A viral load-based model for epidemic spread on spatial networks
title_full A viral load-based model for epidemic spread on spatial networks
title_fullStr A viral load-based model for epidemic spread on spatial networks
title_full_unstemmed A viral load-based model for epidemic spread on spatial networks
title_sort viral load-based model for epidemic spread on spatial networks
publisher AIMS Press
publishDate 2021
url https://doaj.org/article/fe33b47190524aca9ef70be5e596729a
work_keys_str_mv AT nadialoy aviralloadbasedmodelforepidemicspreadonspatialnetworks
AT andreatosin aviralloadbasedmodelforepidemicspreadonspatialnetworks
AT nadialoy viralloadbasedmodelforepidemicspreadonspatialnetworks
AT andreatosin viralloadbasedmodelforepidemicspreadonspatialnetworks
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