Dose-Dependent Response to the Environmental Pollutant Dichlorodipheniletylhene (DDE) in HepG2 Cells: Focus on Cell Viability and Mitochondrial Fusion/Fission Proteins

Dose-Dependent Response to the Environmental Pollutant Dichlorodipheniletylhene (DDE) in HepG2 Cells: Focus on Cell Viability and Mitochondrial Fusion/Fission Proteins

Dichlorodiphenyldichloroethylene (DDE), the primary persistent metabolite of dichlorodiphenyltrichloroethane (DDT), has toxic effects on cells, but its dose-dependent impact on mitochondrial proteins involved in mitochondrial fusion and fission processes associated with cell viability impairment has...

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Bibliographic Details
Main Authors: Mario Alberto Burgos Aceves, Vincenzo Migliaccio, Marilena Lepretti, Gaetana Paolella, Ilaria Di Gregorio, Serena Penna, Caterina Faggio, Lillà Lionetti
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
environmental pollutants
hepatocytes
mitochondria
Mfn2
DRP1
SOD
Chemical technology
TP1-1185
Online Access:https://doaj.org/article/fe3a60d5e0f2429cac4687166c4e9349
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https://doaj.org/article/fe3a60d5e0f2429cac4687166c4e9349

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