Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.

Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. Given the role of this gene in viral defense, we sought to explore the poss...

Full description

Saved in:
Bibliographic Details
Main Authors: Anatoly Urisman, Ross J Molinaro, Nicole Fischer, Sarah J Plummer, Graham Casey, Eric A Klein, Krishnamurthy Malathi, Cristina Magi-Galluzzi, Raymond R Tubbs, Don Ganem, Robert H Silverman, Joseph L DeRisi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2006
Subjects:
Online Access:https://doaj.org/article/fe3f8c4939fb4609b265344ee8a99a5d
Tags: Add Tag
No Tags, Be the first to tag this record!