Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP

Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP

How archaeal viruses perturb host transcription machinery is poorly understood. Here, the authors provide evidence that the archaeo-viral transcription factor ORF145/RIP targets host RNA polymerase, repressing its activity.

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Autores principales: Carol Sheppard, Fabian Blombach, Adam Belsom, Sarah Schulz, Tina Daviter, Katherine Smollett, Emilie Mahieu, Susanne Erdmann, Philip Tinnefeld, Roger Garrett, Dina Grohmann, Juri Rappsilber, Finn Werner
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/fe48d2500b7346f9935066ca430c0d80
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spelling oai:doaj.org-article:fe48d2500b7346f9935066ca430c0d802021-12-02T15:35:44ZRepression of RNA polymerase by the archaeo-viral regulator ORF145/RIP10.1038/ncomms135952041-1723https://doaj.org/article/fe48d2500b7346f9935066ca430c0d802016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13595https://doaj.org/toc/2041-1723How archaeal viruses perturb host transcription machinery is poorly understood. Here, the authors provide evidence that the archaeo-viral transcription factor ORF145/RIP targets host RNA polymerase, repressing its activity.Carol SheppardFabian BlombachAdam BelsomSarah SchulzTina DaviterKatherine SmollettEmilie MahieuSusanne ErdmannPhilip TinnefeldRoger GarrettDina GrohmannJuri RappsilberFinn WernerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carol Sheppard
Fabian Blombach
Adam Belsom
Sarah Schulz
Tina Daviter
Katherine Smollett
Emilie Mahieu
Susanne Erdmann
Philip Tinnefeld
Roger Garrett
Dina Grohmann
Juri Rappsilber
Finn Werner
Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
description How archaeal viruses perturb host transcription machinery is poorly understood. Here, the authors provide evidence that the archaeo-viral transcription factor ORF145/RIP targets host RNA polymerase, repressing its activity.
format article
author Carol Sheppard
Fabian Blombach
Adam Belsom
Sarah Schulz
Tina Daviter
Katherine Smollett
Emilie Mahieu
Susanne Erdmann
Philip Tinnefeld
Roger Garrett
Dina Grohmann
Juri Rappsilber
Finn Werner
author_facet Carol Sheppard
Fabian Blombach
Adam Belsom
Sarah Schulz
Tina Daviter
Katherine Smollett
Emilie Mahieu
Susanne Erdmann
Philip Tinnefeld
Roger Garrett
Dina Grohmann
Juri Rappsilber
Finn Werner
author_sort Carol Sheppard
title Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
title_short Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
title_full Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
title_fullStr Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
title_full_unstemmed Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
title_sort repression of rna polymerase by the archaeo-viral regulator orf145/rip
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/fe48d2500b7346f9935066ca430c0d80
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