Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

ABSTRACT Primary infection with human cytomegalovirus (HCMV) results in a lifelong infection due to its ability to establish latent infection, with one characterized viral reservoir being hematopoietic cells. Although reactivation from latency causes serious disease in immunocompromised individuals,...

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Autores principales: Miri Shnayder, Aharon Nachshon, Benjamin Krishna, Emma Poole, Alina Boshkov, Amit Binyamin, Itay Maza, John Sinclair, Michal Schwartz, Noam Stern-Ginossar
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
cytomegalovirus
gene expression
latency
single-cell RNA-seq
transcriptome
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/fe4be3636745448a895fb1aea3a70ad7
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