Variants in the FFAR1 gene are associated with beta cell function.

Variants in the FFAR1 gene are associated with beta cell function.

<h4>Background</h4>The FFAR1 receptor is expressed mainly in pancreatic beta cells and is activated by medium to long chain free fatty acids (FFAs), as well as by thiazolidinediones, resulting in elevated Ca(2+) concentrations and promotion of insulin secretion. These properties suggest...

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Autores principales: Martins Kalis, Per Levéen, Valeriya Lyssenko, Peter Almgren, Leif Groop, Corrado M Cilio
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fe4f56f92d6d4bce9fca8e2accaf2c31
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