Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice
The use of tumour exosome-activated dendritic cell (DC) immunotherapy shows promise for the treatment of large established tumours. Here, the authors generate alarmin HMGN1-attached tumour exosomes which significantly improve therapy efficacy by boosting DC activation in several preclinical mouse mo...
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Autores principales: | Bingfeng Zuo, Han Qi, Zhen Lu, Lu Chen, Bo Sun, Rong Yang, Yang Zhang, Zhili Liu, Xianjun Gao, Abin You, Li Wu, Renwei Jing, Qibing Zhou, HaiFang Yin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/fe4fbc85947e42be8068f1782617b5b6 |
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