Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis

Background: Unilateral vocal palsy (UVFP) affects the voice and swallowing function and could be treated by various materials to achieve improved mucosal wave and better closure during phonation. Injection laryngoplasty is considered an exemplary method for these patients and could be injected as ea...

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Autores principales:	Wen-Dien Chang, Sheng-Hwa Chen, Ming-Hsui Tsai, Yung-An Tsou
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	autologous fat injection laryngoplasty unilateral vocal fold paralysis acoustic analysis Medicine R
Acceso en línea:	https://doaj.org/article/fe53b34c59cd402a81cb89f22de878c3
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spelling	oai:doaj.org-article:fe53b34c59cd402a81cb89f22de878c32021-11-11T17:39:37ZAutologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis10.3390/jcm102150342077-0383https://doaj.org/article/fe53b34c59cd402a81cb89f22de878c32021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5034https://doaj.org/toc/2077-0383Background: Unilateral vocal palsy (UVFP) affects the voice and swallowing function and could be treated by various materials to achieve improved mucosal wave and better closure during phonation. Injection laryngoplasty is considered an exemplary method for these patients and could be injected as early as possible. We conducted a systematic review and meta-analysis for the subjective and objective outcomes of autologous fat injection laryngoplasty (AFIL) and assessed the effects for patients with UVFP. Methods: We searched studies from PubMed and EBSCO databases with PRISMA appraisal to search for articles about the effects of AFIL on UVFP. The published articles were reviewed according to our inclusion and exclusion criteria. The short- and long-term outcomes of perceptual, acoustic analysis, and quality of life were also analyzed by meta-analysis. Results: Eleven articles were reviewed, and seven studies were selected for meta-analysis. AFIL improves the perceptual outcome and some voice parameters in short-term and long-term results, i.e., jitter, shimmer, and maximal phonation time (MPT). It also significantly improved the voice handicap index (VHI) in the long term, suggesting an increase in quality of life. Conclusions: AFIL is considered a reliable treatment method for UVFP and could even last for over 12 months.Wen-Dien ChangSheng-Hwa ChenMing-Hsui TsaiYung-An TsouMDPI AGarticleautologous fat injection laryngoplastyunilateral vocal fold paralysisacoustic analysisMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5034, p 5034 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	autologous fat injection laryngoplasty unilateral vocal fold paralysis acoustic analysis Medicine R
spellingShingle	autologous fat injection laryngoplasty unilateral vocal fold paralysis acoustic analysis Medicine R Wen-Dien Chang Sheng-Hwa Chen Ming-Hsui Tsai Yung-An Tsou Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
description	Background: Unilateral vocal palsy (UVFP) affects the voice and swallowing function and could be treated by various materials to achieve improved mucosal wave and better closure during phonation. Injection laryngoplasty is considered an exemplary method for these patients and could be injected as early as possible. We conducted a systematic review and meta-analysis for the subjective and objective outcomes of autologous fat injection laryngoplasty (AFIL) and assessed the effects for patients with UVFP. Methods: We searched studies from PubMed and EBSCO databases with PRISMA appraisal to search for articles about the effects of AFIL on UVFP. The published articles were reviewed according to our inclusion and exclusion criteria. The short- and long-term outcomes of perceptual, acoustic analysis, and quality of life were also analyzed by meta-analysis. Results: Eleven articles were reviewed, and seven studies were selected for meta-analysis. AFIL improves the perceptual outcome and some voice parameters in short-term and long-term results, i.e., jitter, shimmer, and maximal phonation time (MPT). It also significantly improved the voice handicap index (VHI) in the long term, suggesting an increase in quality of life. Conclusions: AFIL is considered a reliable treatment method for UVFP and could even last for over 12 months.
format	article
author	Wen-Dien Chang Sheng-Hwa Chen Ming-Hsui Tsai Yung-An Tsou
author_facet	Wen-Dien Chang Sheng-Hwa Chen Ming-Hsui Tsai Yung-An Tsou
author_sort	Wen-Dien Chang
title	Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
title_short	Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
title_full	Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
title_fullStr	Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
title_full_unstemmed	Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
title_sort	autologous fat injection laryngoplasty for unilateral vocal fold paralysis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/fe53b34c59cd402a81cb89f22de878c3
work_keys_str_mv	AT wendienchang autologousfatinjectionlaryngoplastyforunilateralvocalfoldparalysis AT shenghwachen autologousfatinjectionlaryngoplastyforunilateralvocalfoldparalysis AT minghsuitsai autologousfatinjectionlaryngoplastyforunilateralvocalfoldparalysis AT yungantsou autologousfatinjectionlaryngoplastyforunilateralvocalfoldparalysis
_version_	1718432039029440512

Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis

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