Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature

Background: Brain metastasis from endometrial adenocarcinoma is uncommon, and to the brain stem particularly are quite rare. Different therapeutic modalities for metastatic endometrial cancer to the brain such as surgical resection and radiotherapy have been described. Surgical resection of brain st...

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Autores principales:	Amr El Mohamad, Mohammed Alhoobi, Ahmed Saleh, Firas Hammadi, Bara Wazwaz, Ali Ayyad
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Brain metastases Endometrial cancer Brain stem Pontine Endoscopic endonasal transsphenoidal transclival (EETT) Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/fe53f5c1e9084dd791a3f6d28d3e8d43
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spelling	oai:doaj.org-article:fe53f5c1e9084dd791a3f6d28d3e8d432021-11-04T04:31:27ZRare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature2214-751910.1016/j.inat.2021.101420https://doaj.org/article/fe53f5c1e9084dd791a3f6d28d3e8d432022-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2214751921003327https://doaj.org/toc/2214-7519Background: Brain metastasis from endometrial adenocarcinoma is uncommon, and to the brain stem particularly are quite rare. Different therapeutic modalities for metastatic endometrial cancer to the brain such as surgical resection and radiotherapy have been described. Surgical resection of brain stem lesions is challenging, and there are many surgical approaches described in literature. Endoscopic endonasal transsphenoidal transclival approach has not been widely used for anterior pontine metastasis.Herein, we present a case of 47 years old lady who was diagnosed with metastatic endometrial adenocarcinoma in the form of solitary pontine lesion after 3 years of initial diagnosis of uterine adenocarcinoma, which was operated via endoscopic endonasal transsphenoidal transclival approach followed by radiotherapy. Conclusion: Brain metastasis from endometrial cancer is rare, and its management depends on the number of lesions, the extent of disease and the general condition of the patient. Surgery followed by radiotherapy is a good option in isolated brain lesion with no evidence of extracranial lesion. Surgical resection of pontine lesions is challenging, and we suggest endoscopic endonasal transsphenoidal transclival approach for better exposure and resection.Amr El MohamadMohammed AlhoobiAhmed SalehFiras HammadiBara WazwazAli AyyadElsevierarticleBrain metastasesEndometrial cancerBrain stemPontineEndoscopic endonasal transsphenoidal transclival (EETT)SurgeryRD1-811Neurology. Diseases of the nervous systemRC346-429ENInterdisciplinary Neurosurgery, Vol 27, Iss , Pp 101420- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Brain metastases Endometrial cancer Brain stem Pontine Endoscopic endonasal transsphenoidal transclival (EETT) Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Brain metastases Endometrial cancer Brain stem Pontine Endoscopic endonasal transsphenoidal transclival (EETT) Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429 Amr El Mohamad Mohammed Alhoobi Ahmed Saleh Firas Hammadi Bara Wazwaz Ali Ayyad Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
description	Background: Brain metastasis from endometrial adenocarcinoma is uncommon, and to the brain stem particularly are quite rare. Different therapeutic modalities for metastatic endometrial cancer to the brain such as surgical resection and radiotherapy have been described. Surgical resection of brain stem lesions is challenging, and there are many surgical approaches described in literature. Endoscopic endonasal transsphenoidal transclival approach has not been widely used for anterior pontine metastasis.Herein, we present a case of 47 years old lady who was diagnosed with metastatic endometrial adenocarcinoma in the form of solitary pontine lesion after 3 years of initial diagnosis of uterine adenocarcinoma, which was operated via endoscopic endonasal transsphenoidal transclival approach followed by radiotherapy. Conclusion: Brain metastasis from endometrial cancer is rare, and its management depends on the number of lesions, the extent of disease and the general condition of the patient. Surgery followed by radiotherapy is a good option in isolated brain lesion with no evidence of extracranial lesion. Surgical resection of pontine lesions is challenging, and we suggest endoscopic endonasal transsphenoidal transclival approach for better exposure and resection.
format	article
author	Amr El Mohamad Mohammed Alhoobi Ahmed Saleh Firas Hammadi Bara Wazwaz Ali Ayyad
author_facet	Amr El Mohamad Mohammed Alhoobi Ahmed Saleh Firas Hammadi Bara Wazwaz Ali Ayyad
author_sort	Amr El Mohamad
title	Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
title_short	Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
title_full	Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
title_fullStr	Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
title_full_unstemmed	Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
title_sort	rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/fe53f5c1e9084dd791a3f6d28d3e8d43
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Rare pontine metastasis operated via endoscopic transsphenoidal transclival approach, a case report and brief review of literature

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