TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT

An. experimental research, of infusion solution of Metronidazole at single and repeated administration to the animals (rabbits) was carried out. Distinct signs of toxicity of the researched pattern. in the dose that is ten times higher than maximum, daily dose were determined. It concerns statistica...

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Autores principales:	A. G. Yushkov, N. A. Shulgina, A. A. Gushchina, G. G. Yushkov, M. M. Rasulov, V. V. Benemanskiy, M. M. Boon
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	metronidazole infusion solution toxicity under conditions of animals experiment Science Q
Acceso en línea:	https://doaj.org/article/fe5696e9c16047ba9f6334cbe38de412
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spelling	oai:doaj.org-article:fe5696e9c16047ba9f6334cbe38de4122021-11-23T06:14:23ZTO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT2541-94202587-9596https://doaj.org/article/fe5696e9c16047ba9f6334cbe38de4122012-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1065https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596An. experimental research, of infusion solution of Metronidazole at single and repeated administration to the animals (rabbits) was carried out. Distinct signs of toxicity of the researched pattern. in the dose that is ten times higher than maximum, daily dose were determined. It concerns statistically reliably changed hematologic, biochemical and. electrophysiological indices that are typical for Metronidazole in particular. Only the fact of increase of content of creatinine in blood serum in 2 weeks after the administration, of the preparation should be registered but in this case it can be the signal to stop further administration, of the preparation.A. G. YushkovN. A. ShulginaA. A. GushchinaG. G. YushkovM. M. RasulovV. V. BenemanskiyM. M. BoonScientific Сentre for Family Health and Human Reproduction Problemsarticlemetronidazoleinfusion solutiontoxicity under conditions of animals experimentScienceQRUActa Biomedica Scientifica, Vol 0, Iss 4(2), Pp 216-219 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	metronidazole infusion solution toxicity under conditions of animals experiment Science Q
spellingShingle	metronidazole infusion solution toxicity under conditions of animals experiment Science Q A. G. Yushkov N. A. Shulgina A. A. Gushchina G. G. Yushkov M. M. Rasulov V. V. Benemanskiy M. M. Boon TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT
description	An. experimental research, of infusion solution of Metronidazole at single and repeated administration to the animals (rabbits) was carried out. Distinct signs of toxicity of the researched pattern. in the dose that is ten times higher than maximum, daily dose were determined. It concerns statistically reliably changed hematologic, biochemical and. electrophysiological indices that are typical for Metronidazole in particular. Only the fact of increase of content of creatinine in blood serum in 2 weeks after the administration, of the preparation should be registered but in this case it can be the signal to stop further administration, of the preparation.
format	article
author	A. G. Yushkov N. A. Shulgina A. A. Gushchina G. G. Yushkov M. M. Rasulov V. V. Benemanskiy M. M. Boon
author_facet	A. G. Yushkov N. A. Shulgina A. A. Gushchina G. G. Yushkov M. M. Rasulov V. V. Benemanskiy M. M. Boon
author_sort	A. G. Yushkov
title	TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT
title_short	TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT
title_full	TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT
title_fullStr	TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT
title_full_unstemmed	TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT
title_sort	to the possibility of revealing of side effects of metronidazole (0,5% infusion solution, 100 ml) in experiment
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/fe5696e9c16047ba9f6334cbe38de412
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TO THE POSSIBILITY OF REVEALING OF SIDE EFFECTS OF METRONIDAZOLE (0,5% INFUSION SOLUTION, 100 ML) IN EXPERIMENT

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