Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer

BackgroundPetersen’s hernia is a life-threatening complication after gastrectomy. This study is dedicated to identify risk factors for Petersen’s hernia and compare clinical outcomes between patients receiving early or delayed surgical interventions.MethodsData from all patients who received gastrec...

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Autores principales:	Song Liu, Qiongyuan Hu, Peng Song, Liang Tao, Shichao Ai, Ji Miao, Feng Wang, Xing Kang, Xiaofei Shen, Feng Sun, Xuefeng Xia, Meng Wang, Xiaofeng Lu, Wenxian Guan
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	internal hernia gastrectomy gastric cancer risk factor Petersen’s hernia Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/fe58a694db4c4a10b94088f41189fddc
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spelling	oai:doaj.org-article:fe58a694db4c4a10b94088f41189fddc2021-11-08T05:22:05ZRisk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer2234-943X10.3389/fonc.2021.765509https://doaj.org/article/fe58a694db4c4a10b94088f41189fddc2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.765509/fullhttps://doaj.org/toc/2234-943XBackgroundPetersen’s hernia is a life-threatening complication after gastrectomy. This study is dedicated to identify risk factors for Petersen’s hernia and compare clinical outcomes between patients receiving early or delayed surgical interventions.MethodsData from all patients who received gastrectomy due to gastric cancer were collected. Clinical characteristics were compared between Petersen and non-Petersen groups, bowel necrosis and non-necrotic groups. Propensity score matching (PSM) was conducted to generate two comparative groups. Univariate analysis and multivariate logistic regression were performed for risk factor evaluation.ResultsA total of 24 cases of Petersen’s hernia were identified from 1,481 cases of gastrectomy. PSM demonstrated that lower body mass index [BMI; odds ratio (OR) = 0.2, p < 0.01] and distal gastrectomy (OR = 6.2, p = 0.011) were risk factors for Petersen’s hernia. Longer time interval from emergence visit to laparotomy (p = 0.042) and elevated preoperative procalcitonin (p = 0.033) and C-reactive protein (CRP; p = 0.012) were associated with higher risk of bowel necrosis in Petersen’s hernia. Early surgical intervention resulted in less bowel necrosis rate (p = 0.012) and shorter length of necrotic bowel (p = 0.0041).ConclusionsLow BMI and distal gastrectomy are independent risk factor for Petersen’s hernia after gastrectomy. Curtailing observing time and executing prompt surgery are associated with bowel viability and better outcome in patients with Petersen’s hernia.Song LiuQiongyuan HuPeng SongLiang TaoShichao AiJi MiaoFeng WangXing KangXiaofei ShenFeng SunXuefeng XiaMeng WangXiaofeng LuWenxian GuanWenxian GuanFrontiers Media S.A.articleinternal herniagastrectomygastric cancerrisk factorPetersen’s herniaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	internal hernia gastrectomy gastric cancer risk factor Petersen’s hernia Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	internal hernia gastrectomy gastric cancer risk factor Petersen’s hernia Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Song Liu Qiongyuan Hu Peng Song Liang Tao Shichao Ai Ji Miao Feng Wang Xing Kang Xiaofei Shen Feng Sun Xuefeng Xia Meng Wang Xiaofeng Lu Wenxian Guan Wenxian Guan Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer
description	BackgroundPetersen’s hernia is a life-threatening complication after gastrectomy. This study is dedicated to identify risk factors for Petersen’s hernia and compare clinical outcomes between patients receiving early or delayed surgical interventions.MethodsData from all patients who received gastrectomy due to gastric cancer were collected. Clinical characteristics were compared between Petersen and non-Petersen groups, bowel necrosis and non-necrotic groups. Propensity score matching (PSM) was conducted to generate two comparative groups. Univariate analysis and multivariate logistic regression were performed for risk factor evaluation.ResultsA total of 24 cases of Petersen’s hernia were identified from 1,481 cases of gastrectomy. PSM demonstrated that lower body mass index [BMI; odds ratio (OR) = 0.2, p < 0.01] and distal gastrectomy (OR = 6.2, p = 0.011) were risk factors for Petersen’s hernia. Longer time interval from emergence visit to laparotomy (p = 0.042) and elevated preoperative procalcitonin (p = 0.033) and C-reactive protein (CRP; p = 0.012) were associated with higher risk of bowel necrosis in Petersen’s hernia. Early surgical intervention resulted in less bowel necrosis rate (p = 0.012) and shorter length of necrotic bowel (p = 0.0041).ConclusionsLow BMI and distal gastrectomy are independent risk factor for Petersen’s hernia after gastrectomy. Curtailing observing time and executing prompt surgery are associated with bowel viability and better outcome in patients with Petersen’s hernia.
format	article
author	Song Liu Qiongyuan Hu Peng Song Liang Tao Shichao Ai Ji Miao Feng Wang Xing Kang Xiaofei Shen Feng Sun Xuefeng Xia Meng Wang Xiaofeng Lu Wenxian Guan Wenxian Guan
author_facet	Song Liu Qiongyuan Hu Peng Song Liang Tao Shichao Ai Ji Miao Feng Wang Xing Kang Xiaofei Shen Feng Sun Xuefeng Xia Meng Wang Xiaofeng Lu Wenxian Guan Wenxian Guan
author_sort	Song Liu
title	Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer
title_short	Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer
title_full	Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer
title_fullStr	Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer
title_full_unstemmed	Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer
title_sort	risk factor and surgical outcome of petersen’s hernia after gastrectomy in gastric cancer
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/fe58a694db4c4a10b94088f41189fddc
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Risk Factor and Surgical Outcome of Petersen’s Hernia After Gastrectomy in Gastric Cancer

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