Differential Expression of the Sphingolipid Pathway Is Associated with Sensitivity to the PP2A Activator FTY720 in Colorectal Cancer Cell Lines

Protein phosphatase 2A (PP2A) is a ubiquitously expressed intracellular serine/threonine phosphatase. Deregulation of PP2A is a common event associated with adenocarcinomas of the colon and rectum. We have previously shown that breast cancer cell lines are sensitive to the PP2A activator FTY720, and...

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Bibliographic Details
Main Authors: Peter Sciberras, Laura Grech, Godfrey Grech
Format: article
Language:EN
Published: MDPI AG 2021
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R
Online Access:https://doaj.org/article/fe5a853e96744e33b7f82aa26ef28cdc
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