Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity

Both inhibitory and excitatory input development are shaped by activity, but one may be dependent on the other. Here, the authors examine plasticity of inhibitory inputs in vivo, as well as behavioral consequences in tadpoles where excitatory transmission has been impaired.

Guardado en:

Detalles Bibliográficos
Autores principales:	Hai-yan He, Wanhua Shen, Lijun Zheng, Xia Guo, Hollis T. Cline
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fe7125f9a83347c9871914ef2010d97a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fe7125f9a83347c9871914ef2010d97a
record_format	dspace
spelling	oai:doaj.org-article:fe7125f9a83347c9871914ef2010d97a2021-12-02T15:34:05ZExcitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity10.1038/s41467-018-05125-42041-1723https://doaj.org/article/fe7125f9a83347c9871914ef2010d97a2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05125-4https://doaj.org/toc/2041-1723Both inhibitory and excitatory input development are shaped by activity, but one may be dependent on the other. Here, the authors examine plasticity of inhibitory inputs in vivo, as well as behavioral consequences in tadpoles where excitatory transmission has been impaired.Hai-yan HeWanhua ShenLijun ZhengXia GuoHollis T. ClineNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hai-yan He Wanhua Shen Lijun Zheng Xia Guo Hollis T. Cline Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
description	Both inhibitory and excitatory input development are shaped by activity, but one may be dependent on the other. Here, the authors examine plasticity of inhibitory inputs in vivo, as well as behavioral consequences in tadpoles where excitatory transmission has been impaired.
format	article
author	Hai-yan He Wanhua Shen Lijun Zheng Xia Guo Hollis T. Cline
author_facet	Hai-yan He Wanhua Shen Lijun Zheng Xia Guo Hollis T. Cline
author_sort	Hai-yan He
title	Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
title_short	Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
title_full	Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
title_fullStr	Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
title_full_unstemmed	Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
title_sort	excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/fe7125f9a83347c9871914ef2010d97a
work_keys_str_mv	AT haiyanhe excitatorysynapticdysfunctioncellautonomouslydecreasesinhibitoryinputsanddisruptsstructuralandfunctionalplasticity AT wanhuashen excitatorysynapticdysfunctioncellautonomouslydecreasesinhibitoryinputsanddisruptsstructuralandfunctionalplasticity AT lijunzheng excitatorysynapticdysfunctioncellautonomouslydecreasesinhibitoryinputsanddisruptsstructuralandfunctionalplasticity AT xiaguo excitatorysynapticdysfunctioncellautonomouslydecreasesinhibitoryinputsanddisruptsstructuralandfunctionalplasticity AT hollistcline excitatorysynapticdysfunctioncellautonomouslydecreasesinhibitoryinputsanddisruptsstructuralandfunctionalplasticity
_version_	1718386940617687040

Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity

Ejemplares similares