Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions

Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.

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Detalles Bibliográficos
Autores principales: Kyle Xiong, Jian Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fe7973997a0e4faa966b3de9f6798712
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Descripción
Sumario:Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.