Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions

Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.

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Autores principales: Kyle Xiong, Jian Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fe7973997a0e4faa966b3de9f6798712
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spelling oai:doaj.org-article:fe7973997a0e4faa966b3de9f67987122021-12-02T17:02:17ZRevealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions10.1038/s41467-019-12954-42041-1723https://doaj.org/article/fe7973997a0e4faa966b3de9f67987122019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12954-4https://doaj.org/toc/2041-1723Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.Kyle XiongJian MaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kyle Xiong
Jian Ma
Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
description Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.
format article
author Kyle Xiong
Jian Ma
author_facet Kyle Xiong
Jian Ma
author_sort Kyle Xiong
title Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
title_short Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
title_full Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
title_fullStr Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
title_full_unstemmed Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
title_sort revealing hi-c subcompartments by imputing inter-chromosomal chromatin interactions
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/fe7973997a0e4faa966b3de9f6798712
work_keys_str_mv AT kylexiong revealinghicsubcompartmentsbyimputinginterchromosomalchromatininteractions
AT jianma revealinghicsubcompartmentsbyimputinginterchromosomalchromatininteractions
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