Myocardial Injury After Temporary Transvenous Cardiac Pacing

Meng Liu,1,2 Pingsheng Wu2 1Emergency Department, Hunan Provincial People’s Hospital, Medical School of Hunan Normal University, Changsha, People’s Republic of China; 2Cardiology Department, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of...

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Autores principales:	Liu M, Wu P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	temporary pacemaker temporary transvenous cardiac pacing myocardial injury bradycardia perioperative myocardial injury. Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/fe825b3b0abe4165b932bf770ddb8ea7
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spelling	oai:doaj.org-article:fe825b3b0abe4165b932bf770ddb8ea72021-12-02T17:16:50ZMyocardial Injury After Temporary Transvenous Cardiac Pacing1178-203Xhttps://doaj.org/article/fe825b3b0abe4165b932bf770ddb8ea72021-05-01T00:00:00Zhttps://www.dovepress.com/myocardial-injury-after-temporary-transvenous-cardiac-pacing-peer-reviewed-fulltext-article-TCRMhttps://doaj.org/toc/1178-203XMeng Liu,1,2 Pingsheng Wu2 1Emergency Department, Hunan Provincial People’s Hospital, Medical School of Hunan Normal University, Changsha, People’s Republic of China; 2Cardiology Department, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence: Pingsheng WuCardiology Department, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Road, Guangzhou, People’s Republic of ChinaTel +86 02061641502Email wupingshengnf@sina.comIntroduction: Temporary transvenous cardiac pacing (TTCP) can lead to potential penetration and occasional perforation of the right ventricular wall. No study to date has analyzed the effect of TTCP on myocardial injury by cardiac troponin (cTn) measurement. The present study was designed to investigate perioperative myocardial injury in elective TTCP in noncardiac surgical settings.Patients and Methods: This retrospective study investigated the data collected from August 2018 through March 2020 from 22 eligible patients who underwent elective TTCP for noncardiac procedures. The patients had a median age of 66 (50– 83) years; six (27.3%) of them were women, and all of them had a baseline cTn < 1 upper reference limit (URL). Cardiac biomarker assays were performed before and after TTCP, and their results were compared.Results: After TTCP, cTn > 1 URL was detected in 20 (91%, N=22) patients. Among these 22 patients, paired t-test comparing assay results before and after TTCP lead insertion showed a mean cTn elevation of 3.599 URL (95% CI: 1.566 to 5.632, P< 0.01), and a mean creatine kinase-MB isoform elevation of 0.1550 URL (95% CI: − 0.01239 to 0.3224, P> 0.05).Conclusion: The study demonstrates a high incidence of myocardial injury associated with TTCP, which should be a matter of concern for the involved physicians.Keywords: temporary pacemaker, temporary transvenous cardiac pacing, myocardial injury, bradycardia, perioperative myocardial injuryLiu MWu PDove Medical Pressarticletemporary pacemakertemporary transvenous cardiac pacingmyocardial injurybradycardiaperioperative myocardial injury.Therapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 415-421 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	temporary pacemaker temporary transvenous cardiac pacing myocardial injury bradycardia perioperative myocardial injury. Therapeutics. Pharmacology RM1-950
spellingShingle	temporary pacemaker temporary transvenous cardiac pacing myocardial injury bradycardia perioperative myocardial injury. Therapeutics. Pharmacology RM1-950 Liu M Wu P Myocardial Injury After Temporary Transvenous Cardiac Pacing
description	Meng Liu,1,2 Pingsheng Wu2 1Emergency Department, Hunan Provincial People’s Hospital, Medical School of Hunan Normal University, Changsha, People’s Republic of China; 2Cardiology Department, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence: Pingsheng WuCardiology Department, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Road, Guangzhou, People’s Republic of ChinaTel +86 02061641502Email wupingshengnf@sina.comIntroduction: Temporary transvenous cardiac pacing (TTCP) can lead to potential penetration and occasional perforation of the right ventricular wall. No study to date has analyzed the effect of TTCP on myocardial injury by cardiac troponin (cTn) measurement. The present study was designed to investigate perioperative myocardial injury in elective TTCP in noncardiac surgical settings.Patients and Methods: This retrospective study investigated the data collected from August 2018 through March 2020 from 22 eligible patients who underwent elective TTCP for noncardiac procedures. The patients had a median age of 66 (50– 83) years; six (27.3%) of them were women, and all of them had a baseline cTn < 1 upper reference limit (URL). Cardiac biomarker assays were performed before and after TTCP, and their results were compared.Results: After TTCP, cTn > 1 URL was detected in 20 (91%, N=22) patients. Among these 22 patients, paired t-test comparing assay results before and after TTCP lead insertion showed a mean cTn elevation of 3.599 URL (95% CI: 1.566 to 5.632, P< 0.01), and a mean creatine kinase-MB isoform elevation of 0.1550 URL (95% CI: − 0.01239 to 0.3224, P> 0.05).Conclusion: The study demonstrates a high incidence of myocardial injury associated with TTCP, which should be a matter of concern for the involved physicians.Keywords: temporary pacemaker, temporary transvenous cardiac pacing, myocardial injury, bradycardia, perioperative myocardial injury
format	article
author	Liu M Wu P
author_facet	Liu M Wu P
author_sort	Liu M
title	Myocardial Injury After Temporary Transvenous Cardiac Pacing
title_short	Myocardial Injury After Temporary Transvenous Cardiac Pacing
title_full	Myocardial Injury After Temporary Transvenous Cardiac Pacing
title_fullStr	Myocardial Injury After Temporary Transvenous Cardiac Pacing
title_full_unstemmed	Myocardial Injury After Temporary Transvenous Cardiac Pacing
title_sort	myocardial injury after temporary transvenous cardiac pacing
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/fe825b3b0abe4165b932bf770ddb8ea7
work_keys_str_mv	AT lium myocardialinjuryaftertemporarytransvenouscardiacpacing AT wup myocardialinjuryaftertemporarytransvenouscardiacpacing
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Myocardial Injury After Temporary Transvenous Cardiac Pacing

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