Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors

LMO4 has been linked genetically to autism spectrum disorder and intellectual disability. Here, the authors investigate a role of LMO4 in parvalbumin neurons and, specifically, the regulation of dorsal ACC inhibitory circuits.

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Autores principales:	Li Zhang, Zhaohong Qin, Konrad M. Ricke, Shelly A. Cruz, Alexandre F. R. Stewart, Hsiao-Huei Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fe86987c92da4b6d89472524a3eac3c1
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spelling	oai:doaj.org-article:fe86987c92da4b6d89472524a3eac3c12021-12-02T10:59:14ZHyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors10.1038/s41467-020-14813-z2041-1723https://doaj.org/article/fe86987c92da4b6d89472524a3eac3c12020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14813-zhttps://doaj.org/toc/2041-1723LMO4 has been linked genetically to autism spectrum disorder and intellectual disability. Here, the authors investigate a role of LMO4 in parvalbumin neurons and, specifically, the regulation of dorsal ACC inhibitory circuits.Li ZhangZhaohong QinKonrad M. RickeShelly A. CruzAlexandre F. R. StewartHsiao-Huei ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Li Zhang Zhaohong Qin Konrad M. Ricke Shelly A. Cruz Alexandre F. R. Stewart Hsiao-Huei Chen Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
description	LMO4 has been linked genetically to autism spectrum disorder and intellectual disability. Here, the authors investigate a role of LMO4 in parvalbumin neurons and, specifically, the regulation of dorsal ACC inhibitory circuits.
format	article
author	Li Zhang Zhaohong Qin Konrad M. Ricke Shelly A. Cruz Alexandre F. R. Stewart Hsiao-Huei Chen
author_facet	Li Zhang Zhaohong Qin Konrad M. Ricke Shelly A. Cruz Alexandre F. R. Stewart Hsiao-Huei Chen
author_sort	Li Zhang
title	Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
title_short	Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
title_full	Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
title_fullStr	Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
title_full_unstemmed	Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
title_sort	hyperactivated ptp1b phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/fe86987c92da4b6d89472524a3eac3c1
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Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors

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