Asymmetric biomimetic transamination of α-keto amides to peptides

Asymmetric transamination of α-keto amides could provide an efficient strategy to synthesise peptides, but has not been well developed yet. Here, the authors design chiral pyridoxamine catalyst and realize the asymmetric biomimetic transamination of α-keto amides, providing access to various peptide...

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Autores principales: Weiqi Cai, Xuelong Qiao, Hao Zhang, Bo Li, Jianhua Guo, Liangliang Zhang, Wen-Wen Chen, Baoguo Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fe90a4183f1e4373aaebb49c05c7f719
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