The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration
ABSTRACT Human immunodeficiency virus (HIV) infection persists despite decades of active antiretroviral therapy (ART), effectively preventing viral eradication. Treatment decreases plasma viral RNA, but viral DNA persists, mostly integrated within the genome of nucleated blood cells. Viral DNA blood...
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Main Authors: | Thibault Mesplède, Jing Leng, Hanh Thi Pham, Jiaming Liang, Yudong Quan, Yingshan Han, Mark A. Wainberg |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Online Access: | https://doaj.org/article/fe9d8ae16b984049b95ad2d548b322fc |
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