The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration

ABSTRACT Human immunodeficiency virus (HIV) infection persists despite decades of active antiretroviral therapy (ART), effectively preventing viral eradication. Treatment decreases plasma viral RNA, but viral DNA persists, mostly integrated within the genome of nucleated blood cells. Viral DNA blood...

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Auteurs principaux: Thibault Mesplède, Jing Leng, Hanh Thi Pham, Jiaming Liang, Yudong Quan, Yingshan Han, Mark A. Wainberg
Format: article
Langue:EN
Publié: American Society for Microbiology 2017
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Accès en ligne:https://doaj.org/article/fe9d8ae16b984049b95ad2d548b322fc
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