White-tailed deer S96 prion protein does not support stable in vitro propagation of most common CWD strains

Abstract PrPC variation at residue 96 (G/S) plays an important role in the epidemiology of chronic wasting disease (CWD) in exposed white-tailed deer populations. In vivo studies have demonstrated the protective effect of serine at codon 96, which hinders the propagation of common CWD strains when e...

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Autores principales: Alicia Otero, Camilo Duque Velásquez, Judd Aiken, Debbie McKenzie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/feabaed0ca0c469995e0ee56a430bf75
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