Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment

Background: Barleria cristata Linn. belongs to the family Acanthaceae and is commonly known as Raktajhinti and VajraDanti. It is widely distributed in countries, such as India, Nepal, Bangladesh, Pakistan, and Asian tropical regions. This plant has been observed to bear multifarious ethnomedical use...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bhuwan Chandra Joshi, Neha Panthri, Nondita Prasad, Jaswinder Kaur Virk
Formato:	article
Lenguaje:	EN
Publicado:	Mazandaran University of Medical Sciences 2021
Materias:	barleria cristata linn. pharmacognostic standardization physicochemical analysis Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/feac2a3f1d5e474283e79de1643a96af
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:feac2a3f1d5e474283e79de1643a96af
record_format	dspace
spelling	oai:doaj.org-article:feac2a3f1d5e474283e79de1643a96af2021-11-07T16:10:07ZPharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment2423-4494https://doaj.org/article/feac2a3f1d5e474283e79de1643a96af2021-02-01T00:00:00Zhttps://pbr.mazums.ac.ir/article-1-358-en.htmlhttps://doaj.org/toc/2423-4494Background: Barleria cristata Linn. belongs to the family Acanthaceae and is commonly known as Raktajhinti and VajraDanti. It is widely distributed in countries, such as India, Nepal, Bangladesh, Pakistan, and Asian tropical regions. This plant has been observed to bear multifarious ethnomedical uses in treating lung disorders, inflammatory conditions, toothache, anemia, and snakebite. A wide range of major chemical constituents, such as triterpenes, phenolic compounds, flavonoids, and glycosides are reported to be present in this plant. The plant exhibited diverse pharmacological actions, such as anti-inflammatory, antibacterial, antifungal, and antioxidant activities. The literature revealed insufficient information concerning the standardization of Barleria cristata Linn. Objectives: The present study aimed to explore the pharmacognostic and phytochemical characteristics of Barleria cristata Linn. (leaf). Methods: The present study addressed quality control parameters, including loss on drying, ash values, extractive values, pharmacognostic parameters (e.g. macroscopic & microscopic characters and powder microscopy) as per the World Health Organization (WHO) guidelines. Results: Biochemical analysis revealed total ash (16.11±0.38), acid insoluble ash (1.50±0.18), water-soluble ash (11.10±0.23), alcohol-soluble extractive (19.34±0.79), and water-soluble extractive (25.06±0.17), respectively. The transverse section of the leaf revealed the presence of the epidermis, covering trichomes, vascular bundle, and so on. The other parameters such as phytochemical investigation, fluorescence analysis, and thin-layer chromatography were also performed to explore the crucial values of these examinations. Conclusion: The obtained data would be useful in the future for preparing a monograph for the authentication and standardization of this crude drug.Bhuwan Chandra Joshi Neha PanthriNondita PrasadJaswinder Kaur VirkMazandaran University of Medical Sciencesarticlebarleria cristata linn.pharmacognostic standardizationphysicochemical analysisTherapeutics. PharmacologyRM1-950ENPharmaceutical and Biomedical Research, Vol 7, Iss 3, Pp 191-200 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	barleria cristata linn. pharmacognostic standardization physicochemical analysis Therapeutics. Pharmacology RM1-950
spellingShingle	barleria cristata linn. pharmacognostic standardization physicochemical analysis Therapeutics. Pharmacology RM1-950 Bhuwan Chandra Joshi Neha Panthri Nondita Prasad Jaswinder Kaur Virk Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment
description	Background: Barleria cristata Linn. belongs to the family Acanthaceae and is commonly known as Raktajhinti and VajraDanti. It is widely distributed in countries, such as India, Nepal, Bangladesh, Pakistan, and Asian tropical regions. This plant has been observed to bear multifarious ethnomedical uses in treating lung disorders, inflammatory conditions, toothache, anemia, and snakebite. A wide range of major chemical constituents, such as triterpenes, phenolic compounds, flavonoids, and glycosides are reported to be present in this plant. The plant exhibited diverse pharmacological actions, such as anti-inflammatory, antibacterial, antifungal, and antioxidant activities. The literature revealed insufficient information concerning the standardization of Barleria cristata Linn. Objectives: The present study aimed to explore the pharmacognostic and phytochemical characteristics of Barleria cristata Linn. (leaf). Methods: The present study addressed quality control parameters, including loss on drying, ash values, extractive values, pharmacognostic parameters (e.g. macroscopic & microscopic characters and powder microscopy) as per the World Health Organization (WHO) guidelines. Results: Biochemical analysis revealed total ash (16.11±0.38), acid insoluble ash (1.50±0.18), water-soluble ash (11.10±0.23), alcohol-soluble extractive (19.34±0.79), and water-soluble extractive (25.06±0.17), respectively. The transverse section of the leaf revealed the presence of the epidermis, covering trichomes, vascular bundle, and so on. The other parameters such as phytochemical investigation, fluorescence analysis, and thin-layer chromatography were also performed to explore the crucial values of these examinations. Conclusion: The obtained data would be useful in the future for preparing a monograph for the authentication and standardization of this crude drug.
format	article
author	Bhuwan Chandra Joshi Neha Panthri Nondita Prasad Jaswinder Kaur Virk
author_facet	Bhuwan Chandra Joshi Neha Panthri Nondita Prasad Jaswinder Kaur Virk
author_sort	Bhuwan Chandra Joshi
title	Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment
title_short	Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment
title_full	Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment
title_fullStr	Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment
title_full_unstemmed	Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment
title_sort	pharmacognostic and physico-chemical investigation of barleria cristata linn. (leaf) for quality control assessment
publisher	Mazandaran University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/feac2a3f1d5e474283e79de1643a96af
work_keys_str_mv	AT bhuwanchandrajoshi pharmacognosticandphysicochemicalinvestigationofbarleriacristatalinnleafforqualitycontrolassessment AT nehapanthri pharmacognosticandphysicochemicalinvestigationofbarleriacristatalinnleafforqualitycontrolassessment AT nonditaprasad pharmacognosticandphysicochemicalinvestigationofbarleriacristatalinnleafforqualitycontrolassessment AT jaswinderkaurvirk pharmacognosticandphysicochemicalinvestigationofbarleriacristatalinnleafforqualitycontrolassessment
_version_	1718443327666257920

Pharmacognostic and Physico-chemical Investigation of Barleria cristata Linn. (Leaf) for Quality Control Assessment

Ejemplares similares