Effect of spironolactone use in pulmonary arterial hypertension – analysis from pivotal trial databases

Spironolactone, a common diuretic used in the treatment of pulmonary arterial hypertension (PAH), improves cardiopulmonary hemodynamics by attenuating the adverse effects of hyperaldosteronism on endothelin type-B receptor function within pulmonary endothelial cells. Spironolactone has demonstrated...

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Autores principales: Zeenat Safdar, Eunah Cho
Formato: article
Lenguaje:EN
Publicado: SAGE Publishing 2021
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Acceso en línea:https://doaj.org/article/feae43b6f1f849f2a33c67f2dc06260f
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