Effect of spironolactone use in pulmonary arterial hypertension – analysis from pivotal trial databases
Spironolactone, a common diuretic used in the treatment of pulmonary arterial hypertension (PAH), improves cardiopulmonary hemodynamics by attenuating the adverse effects of hyperaldosteronism on endothelin type-B receptor function within pulmonary endothelial cells. Spironolactone has demonstrated...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
| Publié: |
SAGE Publishing
2021
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| Accès en ligne: | https://doaj.org/article/feae43b6f1f849f2a33c67f2dc06260f |
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