Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study

We conducted a phase II study to investigate the feasibility and safety of preoperative radiochemo-therapy experimental fractionation, using intensity-modulated radiation therapy with simultaneous integrated boost (IMRT SIB) to shorten the overall treatment time without dose escalation in intermedia...

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Autores principales:	But-Hadzic Jasna, Boltezar Anja Meden, Skerl Tina, Zadnik Vesna, Velenik Vaneja
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2021
Materias:	rectal cancer imrt simultaneous integrated boost preoperative radiochemotherapy acute toxicity pathologic complete response overall survival disease-free survival local control late toxicity quality of life Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/febaae9b94a741aba822262fbce9c3b7
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spelling	oai:doaj.org-article:febaae9b94a741aba822262fbce9c3b72021-12-05T14:11:10ZPreoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study1581-320710.2478/raon-2021-0028https://doaj.org/article/febaae9b94a741aba822262fbce9c3b72021-11-01T00:00:00Zhttps://doi.org/10.2478/raon-2021-0028https://doaj.org/toc/1581-3207We conducted a phase II study to investigate the feasibility and safety of preoperative radiochemo-therapy experimental fractionation, using intensity-modulated radiation therapy with simultaneous integrated boost (IMRT SIB) to shorten the overall treatment time without dose escalation in intermediate/locally advanced rectal cancer with the aim to improving treatment outcome.But-Hadzic JasnaBoltezar Anja MedenSkerl TinaZadnik VesnaVelenik VanejaSciendoarticlerectal cancerimrtsimultaneous integrated boostpreoperative radiochemotherapyacute toxicitypathologic complete responseoverall survivaldisease-free survivallocal controllate toxicityquality of lifeMedical physics. Medical radiology. Nuclear medicineR895-920ENRadiology and Oncology, Vol 55, Iss 4, Pp 439-448 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	rectal cancer imrt simultaneous integrated boost preoperative radiochemotherapy acute toxicity pathologic complete response overall survival disease-free survival local control late toxicity quality of life Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	rectal cancer imrt simultaneous integrated boost preoperative radiochemotherapy acute toxicity pathologic complete response overall survival disease-free survival local control late toxicity quality of life Medical physics. Medical radiology. Nuclear medicine R895-920 But-Hadzic Jasna Boltezar Anja Meden Skerl Tina Zadnik Vesna Velenik Vaneja Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study
description	We conducted a phase II study to investigate the feasibility and safety of preoperative radiochemo-therapy experimental fractionation, using intensity-modulated radiation therapy with simultaneous integrated boost (IMRT SIB) to shorten the overall treatment time without dose escalation in intermediate/locally advanced rectal cancer with the aim to improving treatment outcome.
format	article
author	But-Hadzic Jasna Boltezar Anja Meden Skerl Tina Zadnik Vesna Velenik Vaneja
author_facet	But-Hadzic Jasna Boltezar Anja Meden Skerl Tina Zadnik Vesna Velenik Vaneja
author_sort	But-Hadzic Jasna
title	Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study
title_short	Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study
title_full	Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study
title_fullStr	Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study
title_full_unstemmed	Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study
title_sort	preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase ii study
publisher	Sciendo
publishDate	2021
url	https://doaj.org/article/febaae9b94a741aba822262fbce9c3b7
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Preoperative intensity-modulated chemoradiotherapy with simultaneous integrated boost in rectal cancer: five-year follow-up results of a phase II study

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