Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

How reproducible human kidney organoids derived from different iPSC lines are, and how faithful they are to human kidney tissue remain unclear. Here, the authors use four human iPSC lines to derive kidney organoids and show how organoid composition is reproducible, comparable to human tissue and of...

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Bibliographic Details
Main Authors: Ayshwarya Subramanian, Eriene-Heidi Sidhom, Maheswarareddy Emani, Katherine Vernon, Nareh Sahakian, Yiming Zhou, Maria Kost-Alimova, Michal Slyper, Julia Waldman, Danielle Dionne, Lan T. Nguyen, Astrid Weins, Jamie L. Marshall, Orit Rosenblatt-Rosen, Aviv Regev, Anna Greka
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
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Online Access:https://doaj.org/article/fec9d1d79cc3436c8e6951c9b267d13d
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https://doaj.org/article/fec9d1d79cc3436c8e6951c9b267d13d

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